國家衛生研究院 NHRI:Item 3990099045/12651
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    题名: Effect of interleukin-1beta and glutathione S-transferase genotypes on the development of gastric mucosa-associated lymphoid tissue lymphoma
    其它题名: Effect of interleukin-1β and glutathione S-transferase genotypes on the development of gastric mucosa-associated lymphoid tissue lymphoma
    作者: Wu, MS;Shun, CT;Huang, SP;Cheng, AL;Chen, LT;Lin, JT
    贡献者: National Institute of Cancer Research
    摘要: e tested whether polymorphic variations in glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and interleukin-1 (IL-1beta and IL-1RN) genes confer susceptibility to mucosa-associated lymphoid tissue lymphomas (MALT) in a Chinese population. The rates of GSTM1, GSTP1, IL-1beta and IL-1RN genotypes did not differ between patients and controls. However, GSTT1 null genotypes were significantly more common in patients with MALT lymphomas (43/75 vs. 138/321, p=0.029; OR=1.8, 95% CI: 1.1-3.0) than in controls. Our results suggest that a glutathione S-transferase defect plays a role in MALT lymphoma.
    日期: 2004-08
    關聯: Haematologica. 2004 Aug;89(8):1015-1017.
    Link to: http://www.haematologica.org/content/89/8/1015.abstract
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0390-6078&DestApp=IC2JCR
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