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日期	题名	關聯
2024-06	UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis	Journal of Autoimmunity. 2024 Jun;146:Article number 103221.
2024-03-27	Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck	Journal of Biomedical Science. 2024 Mar 27;31:Article number 33.
2024-01-15	The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling	Nature Communications. 2024 Jan 15;15:Article number 532.
2023-12-05	Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice	International Journal of Molecular Sciences. 2023 Dec 05;24(24):Article number 17136.
2023-11-01	DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha	Journal of Clinical Investigation. 2023 Nov 01;133(21):Article number e166269.
2023-08-22	ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification	Journal of Biomedical Science. 2023 Aug 22;30:Article number 71.
2023-05-01	DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor	Journal of Immunology. 2023 May 01;210(Suppl. 1):Abstract number 243.04.
2023-04-22	DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia	International Journal of Molecular Sciences. 2023 Apr 22;24(9):Article number 7690.
2023-02-10	Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis	BMC Medicine. 2023 Feb 10;21:Article number 46.
2022-07-27	SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19	EMBO Molecular Medicine. 2022 Jul 27:Article number e15904.
2022-07-18	MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation	Theranostics. 2022 Jul 18;12(12):5744-5760.
2022-02-18	Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice	iScience. 2022 Feb 18;25(2):Article number 103738.
2022-02	Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus	Annals of the Rheumatic Diseases. 2022 Feb;81(2):243-254.
2022-01	Induction of interferon-gamma and tissue inflammation by overexpression of eosinophil cationic protein in T cells and exosomes	Arthritis and Rheumatology. 2022 Jan;74(1):92-104.
2021-10-25	BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus	Theranostics. 2021 Oct 25;11(20):9953-9966.
2020-10-12	Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases	International Journal of Molecular Sciences. 2020 Oct 12;21(20):Article number 7515.
2020-08-12	DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1	Journal of Immunology. 2020 Aug 12;205(6):1644-1652.
2019-11-13	MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus	Cells. 2019 Nov 13;8(11):Article number 1433.
2019-10-22	MAP4K3/GLK in autoimmune disease, cancer and aging	Journal of Biomedical Science. 2019 Oct 22;26:Article number 82.
2019-10	AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus	FASEB Journal. 2019 Oct;3(10):11469-11480.
2019-10	MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1	Cancer Research. 2019 Oct;79(19):4978-4993.
2019-05-30	Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability	International Journal of Molecular Sciences. 2019 May 30;20(11):Article number 2668.
2019-05	MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients	Journal of Immunology. 2019 May;202(1, Suppl. S):Meeting Abstract 132.2.
2019-05	T-cell signaling in Th17-mediated inflammation	Journal of Immunology. 2019 May;202(1, Suppl. S):Meeting Abstract 124.7.
2018-12	RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell	Biochimica et Biophysica Acta-Molecular Cell Research. 2018 Feb;1865(2):259-272.
2018-12	Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation	FASEB Journal. 2018 Dec;32(12):6760-6770.
2018-09-12	GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease	Science Advances. 2018 Sep 12;4(9):Article number eaat5401.
2018-09-06	RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis	International Journal of Molecular Sciences. 2018 Sep 6;19(9):Article number 2646.
2018	MAP4K3 (GLK)	Encyclopedia of Signaling Molecules. 2018 :2947-2951.
2017-11	Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration	Oncogene. 2017 Nov;36(47):6509-6517.
2017-01-07	MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes	Journal of Biomedical Science. 2017 Jan 7;24:Article number 4.
2016-08	Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis	Oncotarget. 2016 Aug;7(36):57593-57605.
2016-08	Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses	European Journal of Immunology. 2016 Aug;46(Suppl. 1):569.
2016-08	Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond	European Journal of Immunology. 2016 Aug;46(Suppl. 1):646.
2016-08	HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to T-cell-mediated type 2 diabetes	European Journal of Immunology. 2016 Aug;46(Suppl. 1):84-85.
2016-07	GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer	Oncotarget. 2016 Jul;7(27):41748-41757.
2016-07	Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase	Oncotarget. 2016 Jul;7(31):49765-49776.
2016-05	Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses	Journal of Immunology. 2016 May;196(1 Suppl.) :Abstract number 203.13.
2016-05	Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond	Journal of Immunology. 2016 May;196(1 Suppl.):Meeting Abstract 202.35.
2016-03-08	Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients	Oncotarget. 2016 Mar 8;7(10):10976-10989.
2016-01	MAP4K family kinases in immunity and inflammation	Advances in Immunology. 2016 Jan;129:277-314.
2014-09-30	Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease	US8846311/2014-09-30
2014-08-06	HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance	Nature Communications. 2014 Aug 6;5:Article number 4602.
2014-04-09	The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck	Nature Communications. 2014 Apr 9;5:Article number 3618.
2014-02-15	Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation	Journal of Immunology. 2014 Feb 15;192(4):1547-1557.
2013-10	Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis	Arthritis and Rheumatism. 2013 Oct;65(10):2573-2582.
2012-08-06	Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker	BMC Medicine. 2012 Aug 6;10(1):Article number 84.
2012-07	Regulation of PKC-theta function by phosphorylation in T cell receptor signaling	Frontiers in Immunology. 2012 Jul;3:Article number 197.
2011-10	The kinase GLK controls autoimmunity and NF-kappa B signaling by activating the kinase PKC-theta in T cells	Nature Immunology. 2011 Oct;12(11):1113-1118.
2009-06	Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis	Hepatology. 2009 Jun;49(6):1962-1971.

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