國家衛生研究院 NHRI:Item 3990099045/11972
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    題名: Sorbitan polyester conjugates for stabilizing water-in-oil emulsions and delivering controlled release of bioactive agents
    作者: Huang, MH;Yi, HC;Chong, PC-S;Leng, CH;Liu, SJ;Chen, HW
    貢獻者: National Institute of Infectious Diseases and Vaccinology
    摘要: A composition in a water-in-oil-in-water (W/O/W) emulsion is disclosed. The composition comprises: (a) a continuous aqueous phase, comprising H2O; (b) an oil phase or an oil shell, dispersed in the continuous aqueous phase; and (c) a hydrophilic polymer, stabilizing an interface between the continuous aqueous phase and the oil phase or the oil shell to form the water-in-oil-in-water (W/O/W) emulsion. The oil phase or the oil shell comprises: (i) oil; (ii) an internal aqueous phase, dispersed within the oil or the oil shell; and (iii) a lipophilic sorbitan-polyester conjugate, stabilizing an interface between the oil and the inner aqueous phase to form a water-in-oil (W/O) emulsion. The lipophilic sorbitan-polyester conjugate comprises: (1) sorbitan; and (2) poly(lactide-co-ε-caprolactone) or polylactic acid (polylactide), conjugated to the sorbitan.
    日期: 2019-01-08
    關聯: US10172945B2/2019-01-08
    Link to: http://v3.espacenet.com/publicationDetails/biblio?CC=US&NR=10172945&KC=B2
    顯示於類別:[黃明熙] 專利
    [莊再成] 專利
    [冷治湘] 專利
    [劉士任] 專利
    [陳信偉] 專利

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