國家衛生研究院 NHRI:Item 3990099045/11972

NHRI > National Institute of Infectious Diseases and Vaccinology > Ming-Hsi Huang > Patents > Item 3990099045/11972

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/11972

Title:	Sorbitan polyester conjugates for stabilizing water-in-oil emulsions and delivering controlled release of bioactive agents
Authors:	Huang, MH;Yi, HC;Chong, PC-S;Leng, CH;Liu, SJ;Chen, HW
Contributors:	National Institute of Infectious Diseases and Vaccinology
Abstract:	A composition in a water-in-oil-in-water (W/O/W) emulsion is disclosed. The composition comprises: (a) a continuous aqueous phase, comprising H2O; (b) an oil phase or an oil shell, dispersed in the continuous aqueous phase; and (c) a hydrophilic polymer, stabilizing an interface between the continuous aqueous phase and the oil phase or the oil shell to form the water-in-oil-in-water (W/O/W) emulsion. The oil phase or the oil shell comprises: (i) oil; (ii) an internal aqueous phase, dispersed within the oil or the oil shell; and (iii) a lipophilic sorbitan-polyester conjugate, stabilizing an interface between the oil and the inner aqueous phase to form a water-in-oil (W/O) emulsion. The lipophilic sorbitan-polyester conjugate comprises: (1) sorbitan; and (2) poly(lactide-co-ε-caprolactone) or polylactic acid (polylactide), conjugated to the sorbitan.
Date:	2019-01-08
Relation:	US10172945B2/2019-01-08
Link to:	http://v3.espacenet.com/publicationDetails/biblio?CC=US&NR=10172945&KC=B2
Appears in Collections:	[Ming-Hsi Huang] Patents [Pele Choi-Sing Chong] Patents [Chih-Hsiang Leng] Patents [Shih-Jen Liu] Patents [Hsin-Wei Chen] Patents

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