國家衛生研究院 NHRI:Item 3990099045/11710
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 858395      線上人數 : 471
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/11710


    題名: The relationship between air pollution and lung cancer in non-smokers in Taiwan
    作者: Tseng, CH;Tsuang, BJ;Chiang, CJ;Ku, KC;Tseng, JS;Yang, TY;Hsu, KH;Chen, KC;Yu, SL;Lee, WC;Liu, TW;Chan, CC;Chang, GC
    貢獻者: National Institute of Cancer Research
    摘要: INTRODUCTION: For never-smokers (smoked <100 lifetime cigarettes), lung cancer (LC) has emerged as an important issue. We aimed to investigate the effects of prevalence changes in tobacco smoking and particulate matter (PM) 2.5 (PM2.5) levels on LC in Taiwan, in relation to contrasting PM2.5 levels, between northern Taiwan (NT) and southern Taiwan (ST). METHODS: We reviewed 371,084 patients with LC to assess smoking prevalence and correlations between the incidence of adenocarcinoma lung cancer (AdLC) and non-AdLC. Two subsets were selected to assess different AdLC stage trends and the effect of PM2.5 on survival of patients with AdLC. RESULTS: From 1995 to 2015, the proportion of male adult ever smokers decreased from 59.4% to 29.9% while the female smoking rate remained low (3.2%-5.3%). AdLC incidence in males and females increased from 9.06 to 23.25 and 7.05 to 24.22 per 100,000 population, respectively. Since 1993, atmospheric visibility in NT improved (from 7.6 to 11.5 km), but deteriorated in ST (from 16.3 to 4.2 km). In 2007, the annual percent change in AdLC stages IB to IV was 0.3% (95% confidence interval [CI], 1.9%-2.6%) in NT, and 4.6% (3.3%-5.8%) in ST; 53% patients with LC had never smoked. Five-year survival rates for never-smokers, those with EGFR wild-type genes, and female patients with AdLC were 12.6% in NT and 4.5% in ST (hazard ratio 0.79, 95% CI; 0.70-0.90). CONCLUSIONS: In Taiwan, >50% patients with LC had never smoked. PM2.5 level changes can affect AdLC incidence and patient survival.
    日期: 2019-05
    關聯: Journal of Thoracic Oncology. 2019 May;14(5):784-792.
    Link to: http://dx.doi.org/10.1016/j.jtho.2018.12.033
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1556-0864&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000465298700018
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85061898090
    顯示於類別:[劉滄梧] 期刊論文

    文件中的檔案:

    檔案 大小格式瀏覽次數
    PUB30664991.pdf1745KbAdobe PDF336檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋