國家衛生研究院 NHRI:Item 3990099045/11002
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 862778      線上人數 : 835
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/11002


    題名: Flexible modulation of CO-Release using various nuclearity of metal carbonyl clusters on graphene oxide for stroke remediation
    作者: Tan, MJ;Pan, HC;Tan, HR;Chai, JW;Lim, QF;Wong, TI;Zhou, X;Hong, ZY;Liao, LD;Kong, KV
    貢獻者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Utilizing the size-dependent adsorption properties of ruthenium carbonyl clusters (Ru-carbon monoxide (CO)) onto graphene oxide (GO), a facile CO-release platform for in situ vasodilation as a treatment for stroke-related vascular diseases is developed. The rate and amount of formation of the CO-release-active Ru(II) (CO)2 species can be modulated by a simple mixing procedure at room temperature. The subsequent thermally induced oxidation of Ru(II) (CO)2 to RuO2 on the GO surface results in the release of CO. Further modulation of thermal and CO-release properties can be achieved via a hybridization of medium- and high-nuclearity of Ru-CO clusters that produces a RuO2 /Ru(II) (CO)2 /(6) Ru-CO-GO composite, where (6) Ru-CO-GO provides a photothermally activated reservoir of Ru(II) (CO)2 species and the combined infrared absorption properties of GO and RuO2 provides photothermal response for in situ CO-release. The RuO2 /Ru(II) (CO)2 /(6) Ru-CO-GO composite does not produce any cytotoxicity and the efficacy of the composite is further demonstrated in a cortical photothrombotic ischemia rat model.
    日期: 2018-03
    關聯: Advanced Healthcare Materials. 2018 Mar;7(5):Article number 1701113.
    Link to: http://dx.doi.org/10.1002/adhm.201701113
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2192-2640&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000426758500022
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85040678880
    顯示於類別:[廖倫德] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    PUB29327505.pdf2948KbAdobe PDF313檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋