國家衛生研究院 NHRI:Item 3990099045/10062

NHRI > Institute of Population Health Sciences > Chung-Yen Lin(1999-2005) > Periodical Articles > Item 3990099045/10062

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/10062

Title:	Dual-compartmental transcriptomic+proteomic analysis of a marine endosymbiosis exposed to environmental change
Other Titles:	Dual-compartmental transcriptomic plus proteomic analysis of a marine endosymbiosis exposed to environmental change
Authors:	Mayfield, AB;Wang, YB;Chen, CS;Chen, SH;Lin, CY
Contributors:	Division of Biostatistics and Bioinformatics
Abstract:	As significant anthropogenic pressures are putting undue stress on the world's oceans, there has been a concerted effort to understand how marine organisms respond to environmental change. Transcriptomic approaches, in particular, have been readily employed to document the mRNA-level response of a plethora of marine invertebrates exposed to an array of simulated stress scenarios, with the tacit and untested assumption being that the respective proteins show a corresponding trend. To better understand the degree of congruency between mRNA and protein expression in an endosymbiotic marine invertebrate, mRNAs and proteins were sequenced from the same samples of the common, Indo-Pacific coral Seriatopora hystrix exposed to stable or upwelling-simulating conditions for one week. Of the 167 proteins down regulated at variable temperature, only 2 were associated with mRNAs that were also differentially expressed between treatments. Of the 378 differentially expressed genes, none were associated with a differentially expressed protein. Collectively, these results highlight the inherent risk of inferring cellular behavior based on mRNA expression data alone and challenge the current, mRNA-focused approach taken by most marine and many molecular biologists.
Date:	2016-12
Relation:	Molecular Ecology. 2016 Dec;25(23):5944-5958.
Link to:	http://dx.doi.org/10.1111/mec.13896
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0962-1083&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000389133700009
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84999025077
Appears in Collections:	[Chung-Yen Lin(1999-2005)] Periodical Articles

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