國家衛生研究院 NHRI:Items for Author

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Items for Author "Peng, YH"

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Showing 25 items.

Collection	Date	Title	Relation
[謝興邦] 會議論文/會議摘要	2005-03	Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents	-
[謝興邦] 期刊論文	2005-12-29	Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities	-
[謝興邦] 期刊論文	2006-02-09	Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies	-
[伍素瑩] 期刊論文	2006-05-04	Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities	-
[伍素瑩] 期刊論文	2006-08-24	Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease	-
[謝興邦] 期刊論文	2006-10-19	Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists	-
[伍素瑩] 期刊論文	2016-01	Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1	-
[翁紹華] 期刊論文	2016-01	Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[蔣維棠] 期刊論文	2019-12	Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia	-
[謝興邦] 期刊論文	2019-11-27	Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer	-
[謝興邦] 期刊論文	2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	-
[趙宇生(2002-2013)] 期刊論文	2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	-
[陳炯東] 期刊論文	2010-12	Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening	-
[謝興邦] 期刊論文	2013-05	Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules	-
[徐祖安] 期刊論文	2013-05	Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors	-
[伍素瑩] 期刊論文	2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	-
[伍素瑩] 期刊論文	2016-04-12	Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK)	-
[伍素瑩] 期刊論文	2019-04-10	Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants	-
[伍素瑩] 期刊論文	2020-02-10	Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors	-
[郭靜娟] 期刊論文	2021-08-12	Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2)	-
[吳嘉文] 期刊論文	2024-06-07	Enhancing ionic selectivity and osmotic energy by using an ultrathin Zr-MOF-based heterogeneous membrane with trilayered continuous porous structure	-
[謝興邦] 期刊論文	2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	-
[蘇益仁(2002-2015)] 期刊論文	2017-03-21	Low-cell-number, single-tube amplification (STA) of total RNA revealed transcriptome changes from pluripotency to endothelium	-
[翁紹華] 期刊論文	2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	-
[許惠恒] 期刊論文	2024-02-13	Age at onset of type 1 diabetes between puberty and 30 years old is associated with increased diabetic nephropathy risk	-

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Items for Author "Peng, YH"