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    Items for Author "Hsu, JT" 

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    Showing 207 items.

    Collection Date Title Relation Bitstream
    [丘政民(2000-2004)] 期刊論文 2004-08 Inhibition of hepatitis C virus replication by arsenic trioxide -
    [伍素瑩] 期刊論文 2015-10 Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening -
    [伍素瑩] 期刊論文 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities -
    [余冠儀] 期刊論文 2020-06-02 Zika virus NS3 protease pharmacophore anchor model and drug discovery -
    [余冠儀] 期刊論文 2016-09 Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy -
    [喻秋華] 期刊論文 2019-05-28 Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform -
    [岳嶽] 期刊論文 2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems -
    [岳嶽] 期刊論文 2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor -
    [張俊彥] 期刊論文 2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells -
    [徐祖安] 專利 2011-07-26 Hepatitis C virus inhibitors -
    [徐祖安] 專利 2011-06-21 抑制冠狀病毒之醫藥組合物 -
    [徐祖安] 專利 2011-06-21 抑制冠狀病毒之醫藥組合物 -
    [徐祖安] 專利 2011-06-21 抑制冠狀病毒之醫藥組合物 -
    [徐祖安] 專利 2009-06-09 Treatment of coronavirus infection -
    [徐祖安] 專利 2008-02-11 一種抗病毒之醫藥組合物 -
    [徐祖安] 專利 2007-03-01 用於治療黃病毒科病毒感染之醫藥組合物、套組、及包裝產品 -
    [徐祖安] 專利 2006-04-19 用於治療黃病毒科病毒感染之醫藥組合物、套組、及包裝產品 -
    [徐祖安] 專利 2003-12-10 Treatment of flaviviridae infection -
    [徐祖安] 會議論文/會議摘要 2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer -
    [徐祖安] 會議論文/會議摘要 2018-12 Dendritic cell-derived exosomes increase the efficacy of anti-PD-L1 antibody in melanoma model -
    [徐祖安] 會議論文/會議摘要 2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer -
    [徐祖安] 會議論文/會議摘要 2011-03 Potent EGFR tyrosine kinase inhibitors as anticancer agents -
    [徐祖安] 會議論文/會議摘要 2004-10 Emergence of mutation clusters in HCV genome during continuous passage of the virus in Sip-L expressing cells -
    [徐祖安] 會議論文/會議摘要 2003-09-10 Generation of chimeric baculovirus with histidine-tags displayed on the envelope and its purification using immobilized metal affinity chromatography -
    [徐祖安] 會議論文/會議摘要 2003-09-10 Combined use of GAP and AOX1 promoter to enhance the expression of human granulocyte-macrophage colony-stimulating factor in Pichia pastoris -
    [徐祖安] 期刊論文 2022-01-18 Acyl-coenzyme a synthetase long-chain family member 4 is involved in viral replication organelle formation and facilitates virus replication via ferroptosis -
    [徐祖安] 期刊論文 2021-07-30 The effects of Abeta1-42 binding to the SARS-CoV-2 spike protein S1 subunit and angiotensin-converting enzyme 2 -
    [徐祖安] 期刊論文 2021-01 Effect of a neuropilin-1-derived virus receptor trap on enterovirus A71 infection in vitro -
    [徐祖安] 期刊論文 2020-08-20 Discovery of M protease inhibitors encoded by SARS-CoV-2 -
    [徐祖安] 期刊論文 2020-05 Antiviral activity of llama-inspired single domain antibody against Enterovirus A71 -
    [徐祖安] 期刊論文 2018-01-23 Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity -
    [徐祖安] 期刊論文 2017-09-26 Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains -
    [徐祖安] 期刊論文 2016-12 Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer -
    [徐祖安] 期刊論文 2016-07-28 Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors -
    [徐祖安] 期刊論文 2016-05-19 Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses -
    [徐祖安] 期刊論文 2016-02-26 Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development -
    [徐祖安] 期刊論文 2016-01-01 Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors -
    [徐祖安] 期刊論文 2015-06-16 Anchor-based classification and type-C inhibitors for tyrosine kinases -
    [徐祖安] 期刊論文 2015-01 Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity -
    [徐祖安] 期刊論文 2014-11-20 The combination effects of LiCl and the active leflunomide metabolite, A771726, on viral-induced interleukin 6 production and EV-A71 replication -
    [徐祖安] 期刊論文 2014-11 Reticulon 3 interacts with NS4B of the hepatitis C virus and negatively regulates viral replication by disrupting NS4B self-interaction -
    [徐祖安] 期刊論文 2014-05 Cover Picture: Facile identification of dual FLT3–aurora a inhibitors: A computer-guided drug design approach (ChemMedChem 5/2014) -
    [徐祖安] 期刊論文 2014-01-08 Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer -
    [徐祖安] 期刊論文 2013-12 Evolutionarily conserved residues at an oligomerization interface of the influenza A virus neuraminidase are essential for viral survival -
    [徐祖安] 期刊論文 2013-09-22 A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment [Erratum:International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411] -
    [徐祖安] 期刊論文 2013-06 Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities -
    [徐祖安] 期刊論文 2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors -
    [徐祖安] 期刊論文 2013-04-29 A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment -
    [徐祖安] 期刊論文 2013-02-20 Parallel screening of Wild-Type and drug-resistant targets for anti-resistance neuraminidase inhibitors -
    [徐祖安] 期刊論文 2012-08 Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching -
    [徐祖安] 期刊論文 2012-06 EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells -
    [徐祖安] 期刊論文 2012-02 Identification of BPR3P0128 as an Inhibitor of cap-snatching activities of influenza virus -
    [徐祖安] 期刊論文 2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML -
    [徐祖安] 期刊論文 2012-01 A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors -
    [徐祖安] 期刊論文 2011-12 Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism -
    [徐祖安] 期刊論文 2011-06-01 Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells -
    [徐祖安] 期刊論文 2011-06 Synergistic inhibition of enterovirus 71 replication by interferon and rupintrivir -
    [徐祖安] 期刊論文 2011-04-25 Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus -
    [徐祖安] 期刊論文 2011-04 Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors -
    [徐祖安] 期刊論文 2010-04 Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid -
    [徐祖安] 期刊論文 2010-01 BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses -
    [徐祖安] 期刊論文 2009-11 Development of NS3/4A protease-based reporter assay suitable for efficiently assessing hepatitis C virus infection -
    [徐祖安] 期刊論文 2009-07 Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71 -
    [徐祖安] 期刊論文 2009-02 Aurintricarboxylic acid inhibits influenza virus neuraminidase -
    [徐祖安] 期刊論文 2008-12 Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress -
    [徐祖安] 期刊論文 2008-11 Amantadine as a regulator of internal ribosome entry site -
    [徐祖安] 期刊論文 2008-08-01 Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents -
    [徐祖安] 期刊論文 2008-05 Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana -
    [徐祖安] 期刊論文 2008-04-01 A mammalian cell-based reverse two-hybrid system for functional analysis of 3C viral protease of human enterovirus 71 -
    [徐祖安] 期刊論文 2007-09 Sf-Caspase-I-repressed stable cells: resistance to apoptosis and augmentation of recombinant protein production -
    [徐祖安] 期刊論文 2006-02 Stable RNA interference in Spodoptera frugiperda cells by a DNA vector-based method -
    [徐祖安] 期刊論文 2006 Antiviral drug discovery targeting to viral proteases -
    [徐祖安] 期刊論文 2005-11 Emergence of mutation clusters in the HCV genome during sequential viral passages in Sip-L expressing cells -
    [徐祖安] 期刊論文 2005-10 Inhibition of hepatitis C virus replication by antimonial compounds -
    [徐祖安] 期刊論文 2005-08 High-throughput cell-based screening for hepatitis C virus NS3/4A protease inhibitors -
    [徐祖安] 期刊論文 2005-06-05 High-efficiency protein expression mediated by enterovirus 71 internal ribosome entry -
    [徐祖安] 期刊論文 2005-04-22 Anti-HCV activities of selective polyunsaturated fatty acids [Erratum: Biochemical and Biophysical Research Communications. 2004 May;318(1):275-280.] -
    [徐祖安] 期刊論文 2005 Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3 '- digallate (TF3) -
    [徐祖安] 期刊論文 2004-10 Biosynthesis of human-type N-glycans in heterollogous systems -
    [徐祖安] 期刊論文 2004-09-10 Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV -
    [徐祖安] 期刊論文 2004-07-23 Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate [Erratum: Biochemical and Biophysical Research Communications. 2004 Jun;318(4):862-867.] -
    [徐祖安] 期刊論文 2004-07 Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide -
    [徐祖安] 期刊論文 2004-06-11 Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate -
    [徐祖安] 期刊論文 2004-05-21 Anti-HCV activities of selective polyunsaturated fatty acids -
    [徐祖安] 期刊論文 2004-05-17 Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidinies: a novel class of potent enterovirus inhibitors -
    [徐祖安] 期刊論文 2004-03-01 A reporter-based assay for identifying hepatitis C virus inhibitors based on subgenornic replicon cells -
    [徐祖安] 期刊論文 2004 Mutations at KFRDI and VGK domains of enterovirus 71 3C protease affect its RNA binding and proteolytic activities -
    [徐祖安] 期刊論文 2003-10-17 Inhibition of authentic hepatitis C virus replication by sodium stibogluconate -
    [徐祖安] 期刊論文 2003-10 Sequential expression of recombinant proteins and their separate recovery from a Pichia pastoris cultivation -
    [徐祖安] 期刊論文 2003-09 Expression of the gene coding for bacterial hemoglobin improves beta-galactosidase production in a recombinant Pichia pastoris -
    [徐祖安] 期刊論文 2003-06 Formation of enterovirus-like particle aggregates by recombinant baculoviruses co-expressing P1 and 3CD in insect cells -
    [徐祖安] 期刊論文 2003-05-15 Development of a cell-based assay for monitoring specific hepatitis C virus NS3/4A protease activity in mammalian cells -
    [徐祖安] 期刊論文 2002-02-15 The 3C protease activity of enterovirus 71 induces human neural cell apoptosis -
    [徐祖安] 期刊論文 2000-12 A baculovirus superinfection system: Efficient vehicle for gene transfer into Drosophila S2 cells -
    [徐祖安] 期刊論文 1999 Formulation, stability, and delivery of live attenuated vaccines for human use -
    [李岳倫] 期刊論文 2018-10 Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach -
    [李秀珠] 期刊論文 2020-08 Repurposing old drugs as antiviral agents for coronaviruses -
    [葉修華] 期刊論文 2019-02-20 Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice -
    [葉燈光] 會議論文/會議摘要 2019-10 Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer -
    [葉燈光] 會議論文/會議摘要 2017-04 Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation -
    [葉燈光] 期刊論文 2006-11-25 The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes -
    [蔡慧珍] 期刊論文 2024-07-11 Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: A nationwide registry study -
    [蔡慧珍] 期刊論文 2016-10 BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia -
    [蔣維棠] 專利 2014-04-21 作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途 -
    [蔣維棠] 期刊論文 2015-07 Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations -
    [蔣維棠] 期刊論文 2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [蔣維棠] 期刊論文 2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) -
    [謝奉勳] 期刊論文 2024-04 Reducing brain Abeta burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice -
    [謝奉勳] 期刊論文 2022-01-05 The beneficial effects of combining anti-Abeta antibody NP106 and curcumin analog TML-6 on the treatment of Alzheimer’s disease in APP/PS1 mice -
    [謝興邦] 專利 2015-07-31 作為極光激酶抑制劑的稠合雙環嘧啶化合物 -
    [謝興邦] 專利 2015-07-22 作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物 -
    [謝興邦] 專利 2014-10-29 作為極光激酶抑制劑的稠合雙環嘧啶化合物 -
    [謝興邦] 專利 2014-10-21 化合物於製造治療病毒感染的藥物之用途 -
    [謝興邦] 專利 2014-04-29 Quinoline compounds and their use for treating viral infection -
    [謝興邦] 專利 2014-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors -
    [謝興邦] 專利 2013-10-01 喹啉化合物及包含其之治療病毒感染之醫藥組成物 -
    [謝興邦] 專利 2013-08-13 Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors -
    [謝興邦] 專利 2013-02-11 作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物 -
    [謝興邦] 專利 2012-05-11 作為極光激酶抑制劑之稠合雙環嘧啶化合物 -
    [謝興邦] 專利 2012-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors -
    [謝興邦] 專利 2011-07-11 抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物 -
    [謝興邦] 專利 2010-12-01 吲哚化合物 -
    [謝興邦] 專利 2008-12-11 吲哚化合物 -
    [謝興邦] 專利 2008-11-11 Indole compounds -
    [謝興邦] 會議論文/會議摘要 2023-10 Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs -
    [謝興邦] 會議論文/會議摘要 2015-08 Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma -
    [謝興邦] 會議論文/會議摘要 2015-08 Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors -
    [謝興邦] 會議論文/會議摘要 2014-11 Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent -
    [謝興邦] 會議論文/會議摘要 2014-10 Optimization of 5,6-fused pyrimidine-based kinase inhibitors by computer-aided drug design for the treatment of AML -
    [謝興邦] 會議論文/會議摘要 2014-10 Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma -
    [謝興邦] 會議論文/會議摘要 2013-04-07 BPR000K, a novel Aurora kinase inhibitor -
    [謝興邦] 會議論文/會議摘要 2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor -
    [謝興邦] 會議論文/會議摘要 2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 -
    [謝興邦] 會議論文/會議摘要 2013-04 Design and synthesis of Aurora kinase inhibitors as anticancer agents -
    [謝興邦] 會議論文/會議摘要 2012-03-25 Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors -
    [謝興邦] 會議論文/會議摘要 2011-09-23 BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo -
    [謝興邦] 會議論文/會議摘要 2011-03-27 Design and synthesis of potent Aurora kinase inhibitors -
    [謝興邦] 會議論文/會議摘要 2011-03 SAR studies of quinoline derivatives as novel anti-influenza agents -
    [謝興邦] 會議論文/會議摘要 2010-08 Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models -
    [謝興邦] 會議論文/會議摘要 2009-09 Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development -
    [謝興邦] 會議論文/會議摘要 2009-03 Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors -
    [謝興邦] 會議論文/會議摘要 2007-07 Anti-influenza drug discovery -
    [謝興邦] 會議論文/會議摘要 2005-03 Promazine analogues as potential anti SARS-CoV drugs -
    [謝興邦] 會議論文/會議摘要 2005-03 Design, synthesis and sar of indole-based PPAR agonists -
    [謝興邦] 會議論文/會議摘要 2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents -
    [謝興邦] 期刊論文 2023-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer -
    [謝興邦] 期刊論文 2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors -
    [謝興邦] 期刊論文 2019-11-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer -
    [謝興邦] 期刊論文 2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation -
    [謝興邦] 期刊論文 2016-11-29 Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design -
    [謝興邦] 期刊論文 2015-06-29 Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification -
    [謝興邦] 期刊論文 2014-12 BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71 -
    [謝興邦] 期刊論文 2014-08 Ligand efficiency based approach for efficient virtual screening of compound libraries -
    [謝興邦] 期刊論文 2014-05 Facile identification of dual FLT3-Aurora A inhibitors: A computer-guided drug design approach -
    [謝興邦] 期刊論文 2013-06-28 Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor -
    [謝興邦] 期刊論文 2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules -
    [謝興邦] 期刊論文 2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor -
    [謝興邦] 期刊論文 2012-12 An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold -
    [謝興邦] 期刊論文 2012-09 Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization -
    [謝興邦] 期刊論文 2010-06-15 Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification -
    [謝興邦] 期刊論文 2010-02-25 Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives -
    [謝興邦] 期刊論文 2010-02-01 Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor -
    [謝興邦] 期刊論文 2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists -
    [謝興邦] 期刊論文 2009-02-26 Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity -
    [謝興邦] 期刊論文 2008-07 Anti-HSV activity of digitoxin and its possible mechanisms -
    [謝興邦] 期刊論文 2008-03-01 Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold -
    [謝興邦] 期刊論文 2007-12 Strategies of development of antiviral agents directed against influenza virus replication -
    [謝興邦] 期刊論文 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists -
    [謝興邦] 期刊論文 2006-07 Antiviral drug discovery against SARS-CoV -
    [謝興邦] 期刊論文 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies -
    [謝興邦] 期刊論文 2006-01-01 Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system -
    [謝興邦] 期刊論文 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities -
    [賴基銘(2004-2008)] 期刊論文 2007-02-08 Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells -
    [趙宇生(2002-2013)] 會議論文/會議摘要 2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia -
    [趙宇生(2002-2013)] 期刊論文 2012-02 Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents -
    [趙宇生(2002-2013)] 期刊論文 2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency -
    [趙宇生(2002-2013)] 期刊論文 2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists -
    [趙宇生(2002-2013)] 期刊論文 2010-02-23 Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity -
    [鄒倫] 期刊論文 2022-06-21 Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids -
    [鄒倫] 期刊論文 2019-07-11 Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates -
    [鄒倫] 期刊論文 2017-07 Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates -
    [陳志豪] 專利 2012-04-11 咪唑啉酮及咪唑啉硫酮衍生物 -
    [陳志豪] 專利 2012-03-01 C型肝炎病毒抑制劑 -
    [陳志豪] 專利 2011-05-10 Imidazolidinone and imidazolidinethione derivatives -
    [陳志豪] 專利 2011-03-01 Thiourea derivatives -
    [陳志豪] 專利 2010-08-21 硫尿化合物及抑制C型肝炎病毒感染之方法 -
    [陳志豪] 專利 2006-08-01 抗腸病毒化合物 -
    [陳志豪] 專利 2004-11-09 Anti-enterovirus compounds -
    [陳志豪] 期刊論文 2019-04-01 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus -
    [陳志豪] 期刊論文 2017-01 A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide -
    [陳志豪] 期刊論文 2009-11-01 Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors -
    [陳志豪] 期刊論文 2009-08-01 Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors -
    [陳志豪] 期刊論文 2009-04-01 Design, synthesis, and anti-HCV activity of thiourea compounds -
    [陳怡榮] 期刊論文 2008-06-01 A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors -
    [陳振陽] 期刊論文 2014-02 Epstein-Barr virus BALF3 has nuclease activity and mediates mature virion production during the lytic cycle -
    [陳新(2002-2015)] 期刊論文 2005-08-02 Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition -
    [陳新(2002-2015)] 期刊論文 2004-05 Purification and characterization of human prolyl dipeptidase DPPS in Sf9 insect cells -
    [陳炯東] 會議論文/會議摘要 2018-01 Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer -
    [陳炯東] 會議論文/會議摘要 2015-08 Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia -
    [陳炯東] 期刊論文 2022-10-13 Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate -
    [陳炯東] 期刊論文 2020-08 Artificial intelligence approach fighting COVID-19 with repurposing drugs -
    [顏婉菁] 會議論文/會議摘要 2019-10 Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117) -
    [黃明熙] 期刊論文 2021-07-16 Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens -
    [黃智興] 期刊論文 2024-07-04 Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells -
    [黃智興] 期刊論文 2022-01-11 Extracellular HSP90alpha induces MyD88-IRAK complex-associated IKKalpha/Beta−NF-KappaB/IRF3 and JAK2/TYK2−STAT-3 signaling in macrophages for tumor-promoting M2-polarization -
    [黃智興] 期刊論文 2019-12-17 Endothelial-mesenchymal transition harnesses HSP90alpha-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma -

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