國家衛生研究院 NHRI:Item 3990099045/9923
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9923


    Title: Vegetarian diet reduces the risk of hypertension independent of abdominal obesity and inflammation: A prospective study
    Authors: Chuang, SY;Chiu, TH;Lee, CY;Liu, TT;Tsao, CK;Hsiung, CA;Chiu, YF
    Contributors: Division of Biostatistics and Bioinformatics;Division of Health Services and Preventive Medicine
    Abstract: OBJECTIVES: A vegetarian diet may prevent elevation of blood pressures and lower the risk for hypertension through lower degrees of obesity, inflammation, and insulin resistance. This study investigated the association between a vegetarian diet and hypertension incidence in a cohort of Taiwanese adult nonsmokers and examined whether this association was mediated through inflammation, abdominal obesity, or insulin resistance (using fasting glucose as a proxy). METHODS: This matched cohort study was from the 1994-2008 MJ Health Screening Database. Each vegetarian was matched with five nonvegetarians by age, sex, and study site. The analysis included 4109 nonsmokers (3423 nonvegetarians and 686 vegetarians), followed for a median of 1.61 years. The outcome includes hypertension incidence, as well as SBP and DBP levels. Regression analysis was performed to assess the association between vegetarian diet and hypertension incidence or future blood pressure levels in the presence/absence of potential mediators. RESULTS: Vegetarians had a 34% lower risk for hypertension, adjusting for age and sex (odds ratio: 0.66, 95% confidence interval: 0.50-0.87; SBP: -3.3 mmHg, P < 0.001; DBP: -1.5 mmHg, P < 0.001). The results stay statistically significant after further adjustment for C-reactive protein, waist circumference, and fasting glucose (odds ratio: 0.72, 95% confidence interval: 0.55-0.86; SBP: -2.4 mmHg, P < 0.05; DBP: -1.1 mmHg, P < 0.05). The protective association between vegetarian diet and hypertension appeared to be consistent across age groups. CONCLUSION: Taiwanese vegetarians had lower incidence of hypertension than nonvegetarians. Vegetarian diets may protect against hypertension beyond lower abdominal obesity, inflammation, and insulin resistance.
    Date: 2016-11
    Relation: Journal of Hypertension. 2016 Nov;34(11):2164-2171.
    Link to: http://dx.doi.org/10.1097/hjh.0000000000001068
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0263-6352&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000385536600011
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84981510370
    Appears in Collections:[Yen-Feng Chiu] Periodical Articles
    [Chao A. Hsiung] Periodical Articles
    [Shao-Yuan Chuang] Periodical Articles

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