國家衛生研究院 NHRI:Item 3990099045/9885

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Title:	Applications of a rapid and sensitive dengue DUO rapid immunochromatographic test kit as a diagnostic strategy during a dengue type 2 epidemic in an urban city
Authors:	Shih, HI;Hsu, HC;Wu, CJ;Lin, CH;Chang, CM;Tu, YF;Hsieh, CC;Chi, CH;Sung, TC
Contributors:	Division of Infectious Diseases
Abstract:	Dengue infection is a major health problem in tropical and subtropical countries. A prospective observational study in a university-affiliated hospital was conducted between August 2015 and September 2015. Patients who visited the emergency department (ED) with a presentation of any symptoms of dengue were eligible for the dengue non-structural protein 1 (NS1), IgM/IgG rapid immunochromatographic tests and real-time polymerase chain reaction (RT-PCR) to evaluate the performance of the rapid tests. Considering the RT-PCR as the gold standard for the dengue diagnosis, the ideal primary results of sensitivity (80-100%), specificity (60-84%), positive predicted value(75%-95%), and negative predicted value (70-100%) suggested that the NS1-based test with or without a combination of IgM and IgG tests have good diagnostic performances in detecting dengue infections, even in the afebrile or elderly populations.
Date:	2016-07-14
Relation:	PLoS ONE. 2016 Jul 14;11(7):Article number e0158437.
Link to:	http://dx.doi.org/10.1371/journal.pone.0158437
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1932-6203&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000379579500022
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84978629035
Appears in Collections:	[Chi-Jung Wu] Periodical Articles

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