國家衛生研究院 NHRI:Item 3990099045/9634
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 858618      線上人數 : 640
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/9634


    題名: The association between periodontal disease and pancreatic cancer
    作者: Chang, JS;Tsai, CR;Shan, YS;Chen, LT
    貢獻者: National Institute of Cancer Research
    摘要: Background: Despite years of research, the causes of pancreatic cancer have remained largely unknown. Periodontal disease (PD) is an emerging risk factor for various systemic diseases, including cancer. The current study investigated the association between PD (periodontitis, gingivitis, and others) and development of pancreatic cancer. Methods: Using data from the National Health Insurance Research Database of Taiwan, 139,805 subjects with PD and 75,085 subjects without PD were identified. The association between PD and pancreatic cancer was assessed using Cox proportional hazards regression model. Results: Having PD was associated with a higher pancreatic cancer risk (hazard ratio (HR) = 1.55, 95% confidence interval (CI): 1.02-2.33). The higher pancreatic cancer risk associated with PD was observed among those aged 65 years or older (HR = 2.17, 95% CI: 1.03-4.57) and but not among those aged younger than 65 years (HR = 0.83, 95% CI: 0.52-1.34). Further analysis showed that PD remained an independent risk factor for pancreatic cancer after adjusting for diabetes, hyperlipidemia, allergies, viral hepatitis, peptic ulcer, pancreatitis, COPD (as a proxy for cigarette smoking) and alcoholic-related conditions (as a proxy for alcohol drinking). Conclusions: Our analysis showed a significantly positive association between PD and pancreatic cancer risk. Further investigation is needed to explain the underlying biological mechanisms for the positive association between PD and pancreatic cancer.
    日期: 2015-08
    關聯: Cancer Research. 2015 Aug;75:Abstract number 871.
    Link to: http://dx.doi.org/10.1158/1538-7445.am2015-871
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0008-5472&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000371578501323
    顯示於類別:[張書銘] 會議論文/會議摘要
    [陳立宗] 會議論文/會議摘要

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    ISI000371578501323.pdf27KbAdobe PDF402檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋