國家衛生研究院 NHRI:Item 3990099045/9610
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 853213      在线人数 : 716
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/9610


    题名: Hospital-based surveillance of enterovirus 71 in HCM City, Vietnam, 2011-2014
    作者: Luo, ST;Chung, WY;Nhan, LNT;Lien, LB;Khanh, TH;Dan, TNH;Thoa, LPK;Hung, NT;Chiang, PS;Su, IJ;Lee, MS
    贡献者: Division of Infectious Diseases
    摘要: Background: Human enteroviruses are classified into four species (A, B, C and D) and include over 100 serotypes. Since 1997, Enterovirus 71(EV71) usually causes self-limited infections with non-specific symptoms and manifests hand-food-month disease (HFMD) or herpangina in children. EV71 have caused severe life-threatening outbreaks in young children in Asian. EV71 circulation among Vietnamese children was first documented in 2005. Methods & Materials: In 2011, there is a big outbreak of EV71 in Vietnam with more than 5,000 inpatients in Children Hospital No.1 (CH1), and 32 fetal cases. National Health Research Institutes cooperates with CH1 to establish hospital-based surveillance of enterovirus in HCM City in 2011. Children <10 years of age who develop HFMD and were admitted to HCM CH1 were collected throat swabs and sera. Throat swabs were used for virus isolation and Sera were used to measure neutralizing antibody against EV71 in Taiwan NHRI. Results: Enterovirus isolate rate with HFMD-related inpatients including 38.9% (21/54) in 2011, 19.3% (79/409) in 2012, 42.0% (173/412) in 2013 and 12% (12/100) on June, 2014. Among them, EV71 positive rate from 2011 to June, 2014 were 29.6%, 6.8%, 16.0% and 5%, respectively. The age-specific seropositive rates increase from 15.2% at <0.5 years of age to 17.2, 24.0, 29.4, 58.6, 62.3, 66.1, 77.6% at 0.5-0.9, 1-1.9, 2-2.9, 3-3.9, 4-4.9, 5-5.9 and 6-6.9 years of age, respectively. Conclusion: The predominant genotype shifted from C4 in 2011 to B5 in 2013. Risk of EV71 infections in Vietnam increased after 6 months of age. Vietnamese children in HCM City acquired EV71 infections at early age and vaccine development in Vietnam should target young children.
    日期: 2016-04
    關聯: International Journal of Infectious Diseases. 2016 Apr;45(Suppl. 1):303.
    Link to: http://dx.doi.org/10.1016/j.ijid.2016.02.665
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1201-9712&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000374876700609
    显示于类别:[李敏西] 會議論文/會議摘要
    [蘇益仁(2002-2015)] 會議論文/會議摘要

    文件中的档案:

    档案 大小格式浏览次数
    SDO1201971216306440.pdf49KbAdobe PDF530检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈