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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9587


    Title: Prevalence and prognosis of Brugada electrocardiogram patterns in an elderly Han Chinese population: a nation-wide community-based study (HALST cohort)
    Authors: Juang, JM;Chen, CY;Chen, YH;Wu, IC;Hsu, CC;Chen, LN;Tang, FC;Wang, CC;Juan, CC;Chiu, HC;Lo, HM;Chang, IS;Hwang, JJ;Lai, LP;Chiang, FT;Lin, JL;Hsiung, CA
    Contributors: Division of Geriatric Research;Division of Health Services and Preventive Medicine;Division of Biostatistics and Bioinformatics;National Institute of Cancer Research
    Abstract: AIMS: The exact world-wide prevalence of Brugada electrocardiogram (ECG) pattern is still unclear, especially in adults aged 55 years and older. METHODS AND RESULTS: The study was conducted as part of the Healthy Aging Longitudinal Study in Taiwan (HALST). Using a stratified random sampled method, a sample of community-dwelling subjects was recruited from seven community-based regions across Taiwan. All enrolled subjects were follow-up annually and cause of death was documented by citizen death records. A total of 5214 subjects were enrolled (male/female: 2530/2684) with a mean age of 69 +/- 8 years. The overall prevalence of Brugada ECG patterns was 3.32%. Four subjects carried spontaneous Type 1 Brugada ECG pattern, 68 carried Type 2, and 101 carried Type 3. Compared with the world-wide average prevalence of Brugada ECG patterns, the prevalence of spontaneous Type 1 Brugada ECG pattern in subjects from the HALST cohort was similar (0.077 vs. 0.07%) and the combined prevalence of Types 2 and 3 Brugada ECG pattern was 10 times higher (3.24 vs. 0.28%) even the mean age of study subjects was significantly higher (69 +/- 8 vs. 35 +/- 8, P < 0.001). However, all-cause mortality and cardiac mortality rates were not significantly different between subjects with and without Brugada ECG patterns during the 4-year follow-up (log-rank test, P = 0.21, 0.32, respectively). CONCLUSION: The prevalence of Brugada ECG pattern in adults aged 55 years and older in Taiwan was higher than the average world-wide prevalence but was not associated with increased mortality.
    Date: 2015-10
    Relation: Europace. 2015 Oct;17(Suppl. 2):ii54-ii62.
    Link to: http://dx.doi.org/10.1093/europace/euv141
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1099-5129&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000370282800008
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84959871818
    Appears in Collections:[吳易謙] 期刊論文
    [許志成] 期刊論文
    [熊昭] 期刊論文
    [張憶壽] 期刊論文

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