國家衛生研究院 NHRI:Item 3990099045/9455
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 911415      在线人数 : 930
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/9455


    题名: Risks of death and stroke in patients undergoing hemodialysis with new-onset atrial fibrillation: A competing-risk analysis of a nationwide cohort
    作者: Shih, CJ;Ou, SM;Chao, PW;Kuo, SC;Lee, YJ;Yang, CY;Tarng, DC;Lin, CC;Huang, PH;Li, SY;Chen, YT
    贡献者: Division of Infectious Diseases
    摘要: BACKGROUND: -Whether oral anticoagulant (OAC) use should be considered in patients undergoing hemodialysis with atrial fibrillation (AF) remains controversial due to uncertainty regarding risk-benefit assessments. The purpose of this study was to investigate the risk of ischemic stroke in patients undergoing hemodialysis with new-onset AF, compared with those without arrhythmia. METHODS AND RESULTS: -This nationwide, population-based, propensity score-matched cohort study used data from Taiwan's National Health Insurance Research Database during 1998-2011 for patients on hemodialysis with new-onset non-valvular AF and matched subjects without arrhythmia. The clinical endpoints were ischemic stroke (fatal or non-fatal), all-cause death, and other serious adverse cardiovascular events. Compared with the matched cohort, patients with AF (n = 6,772) had higher risks of ischemic stroke (adjusted hazard ratio [aHR] 1.27, 95% confidence interval [CI] 1.13-1.43), all-cause death (aHR 1.59, 95% CI 1.52-1.67), in-hospital cardiovascular death (aHR 1.83, 95% CI 1.71-1.94), myocardial infarction (aHR 1.33, 95% CI 1.17-1.51), and hospitalization for heart failure (aHR 1.90, 95% CI 1.76-2.05). After considering in-hospital death as a competing risk, AF significantly increased the risk of heart failure (HR 1.56, 95% CI 1.45-1.68), but not those of ischemic stroke and myocardial infarction. Additionally, the predictive value of the CHA2DS2-VASc score for ischemic stroke was diminished in the competing risk model. CONCLUSIONS: -The risk of stroke was only modestly higher in patients undergoing hemodialysis with new-onset AF than in those without AF, and it became insignificant when accounting for the competing risk of in-hospital death.
    日期: 2016-01-19
    關聯: Circulation. 2016 Jan 19;133(3):265-272.
    Link to: http://dx.doi.org/10.1161/circulationaha.115.018294
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0009-7322&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000368540900006
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84955647296
    显示于类别:[郭書辰] 期刊論文

    文件中的档案:

    档案 大小格式浏览次数
    PUB26680239.pdf2915KbAdobe PDF347检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈