國家衛生研究院 NHRI:Item 3990099045/9444
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    题名: Self-concentrating buoyant glass microbubbles for high sensitivity immunoassays
    作者: Juang, DS;Hsu, CH
    贡献者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Here, we report the novel application of a material with self-concentrating properties for enhancing the sensitivity of immunoassays. Termed as glass microbubbles, they are antibody functionalized buoyant hollow glass microspheres that simultaneously float and concentrate into a dense monolayer when dispensed in a liquid droplet. This self-concentrating charactaristic of the microbubbles allow for autonomous signal localization, which translates to a higher sensitivity compared to other microparticle-based immunoassays. We then demonstrated a "microbubble array" platform consisting of the glass microbubbles floating in a microfluidic liquid hemisphere array for performing multiplex immunoassays.
    日期: 2016-01-26
    關聯: Lab on a Chip. 2016 Jan 26;16(3):459-464.
    Link to: http://dx.doi.org/10.1039/c5lc01005e
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1473-0197&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000368858700005
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84956722570
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