國家衛生研究院 NHRI:Item 3990099045/9441
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9441


    Title: Mesoporous Europium-Doped Titania Nanoparticles (Eu-MTNs) for luminescence-based intracellular bio-imaging
    Authors: Chen, KC;Dutta, S;Yannauchi, Y;Alshehri, SM;Nguyen, MT;Yonezawa, T;Shen, KH;Wu, KCW
    Contributors: Institute of Biomedical Engineering and Nanomedicine
    Abstract: Monodisperse and mesoporous europium (Eu)-doped titania nanoparticles (denoted as Eu-MTNs) were prepared by a co-synthesis method with the presence of a cationic surfactant (i.e., CTAB). A maximum loading amount of 8 mol% of Eu could be successfully incorporated into the framework of MTNs. The synthesized Eu-MTNs samples were characterized with X-ray diffraction (XRD) and scanning electron microscopy (SEM), with their luminescent property examined by photoluminescence (PL). Under ultraviolet irradiation, the Eu-MTNs samples exhibit several characteristic luminescence corresponding to D-5(0)-F-7(j) for Eu+3 ions, which can be attributed to the energy transfer from titania nanocrystallite to Eu3+ ions dispersed in amorphous mesoporous titania region. The potential intracellular bio-imaging application of the synthesized Eu-MTN nanoparticles was demonstrated with a breast cancer cell line (i.e., BT-20). High biocompatibility and strong luminescence of the Eu-MTNs show great potential in biomedical applications.
    Date: 2015-12
    Relation: Journal of Nanoscience and Nanotechnology. 2015 Dec;15(12):9802-9806.
    Link to: http://dx.doi.org/10.1166/jnn.2015.12329
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000365555000063
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84956636007
    Appears in Collections:[Chia-Wen Wu] Periodical Articles

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