國家衛生研究院 NHRI:Item 3990099045/9363
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    題名: Ankle-brachial index and brachial-ankle pulse wave velocity jointed to predict mortality in a community study
    作者: Chuang, SY;Sung, SH;Cheng, HM;Hsu, PF;Chou, P;Chen, CH
    貢獻者: Division of Health Services and Preventive Medicine
    摘要: Background: Pulse volume recordings and blood pressures at arms and ankles can be obtained automatically and simultaneously to allow fast measurements of the brachial-ankle pulse wave velocity and the ankle-brachial index. We evaluated the association between ankle-brachial index, brachial-ankle pulse and mortality in a community. Methods: A total of 1329 residents (≥40 yrs) in Kinmen completed a health survey, including interview, physical examination, blood test, and the measurements of brachial-ankle pulse wave velocity and ankle-brachial index in 10 working days. By linking with the National Death Registry, we retrieved the dates and causes of death of all participants until December 31, 2012. The median followup durations was 10 years. The Cox proportional hazard model was used to estimate the hazard ratios (HRs) of abnormal Ankle-brachial index (ABI 1.3) and high brachial-ankle pulse wave velocity (baPWV ≥1670 cm/sec) for total/cardiovascular mortality. Results: A total of 115 deaths occurred and 26 cardiovascular mortality during the 10-yrs (median) fallow period. The prevalence of abnormal ABI and high baPWV were 3.09% (n=41) and 26.34% (n=350), respectively. The total mortality was 4.1 per 1000 persons for normal PWV and normal ABI, 20.6 per 1000 PYS for normal PWV and abnormal ABI, 19.6 per 1000 PYS for high PWV and normal ABI, and 48.3 per 1000 PYs for high PWV and abnormal ABI. The crude hazard ratio (HR) of 12.43 (95% confidence intervals: 6.03–25.6) for high baPWV and abnormal ABI, 4.92 (3.30–7.32) for high PWV and normal ABI, and 5.16 (1.85– 14.42) for normal baPWV and abnormal ABI, compared to those with normal ABI and normal baPWV. In the multivariate model, the HRs of total mortality was 2.82 (1.12–7.11) high baPWV and abnormal ABI, was 1.87 (1.09–3.21) for high PWV and normal ABI, and was 2.67 (0.87–8.19) for normal baPWV and abnormal ABI. Conclusion: Ankle-brachial index and brachial-ankle pulse wave velocity jointed to significantly predict total and cardiovascular mortality in a general community cohort.
    日期: 2015-08
    關聯: European Heart Journal. 2015 Aug;36(Suppl.1):1015-1016.
    Link to: http://dx.doi.org/10.1093/eurheartj/ehv401
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0195-668X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000361205106619
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