國家衛生研究院 NHRI:Item 3990099045/9091
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    題名: Pyrrolidine derivatives
    作者: Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
    貢獻者: Institute of Biotechnology and Pharmaceutical Research
    摘要: FIELD: chemistry.SUBSTANCE: invention relates to pyrrolidine derivatives of formula:where: each of R, R, R, R, Rand Rindependently denotes H, Calkyl; Rdenotes Calkyl, a 5-6-member monocyclic aromatic heteroaryl, having one or two heteroatoms selected from N, S, optionally substituted with Calkyl; R denotes H, Calkyl; or Rand R, together with a N with which they are attached, form a 5-8-member monocyclic, saturated or unsaturated ring, optionally including a second hateroatom selected from N, S, O, optionally substituted with a halogen, CN, -OR', Calkyl, hydroxyCalkyl, CalkoxyCalkyl, -S(O)R', -C(O)OR', or form a 8-12-member bicyclic, saturated or unsaturated ring; R' denotes H, Calkyl; m and n are independently equal to 0, 1, 2 or 3; X denotes NR, Rdenotes H. The compounds are used in a method of inhibiting dipeptidyl peptidase IV.EFFECT: obtaining pyrrolidine derivatives.13 cl, 2 dwg, 1 tbl, 26 ex
    日期: 2013-09-27
    關聯: RU2494094C2/2013-09-27
    Link to: http://v3.espacenet.com/publicationDetails/biblio?CC=RU&NR=2494094&KC=C2
    顯示於類別:[蔣維棠] 專利
    [趙宇生(2002-2013)] 專利

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