本發明揭示一抑制一氧化氮產生以及腫瘤壞死因子α(TNFα)的方法,以及投予下列化合物一有效劑量以治療冠狀病毒感染之方法: 其中R1、R2、R3、R4、R5、A以及X將於說明書中定義。 This invention relates to a method of inhibiting NO production and TNF and treating coronaviral infection by administering an effective amount of a compound of the following formula: wherein R1, R2, R3, R4, R5, A, and X are as defined herein.