國家衛生研究院 NHRI:Item 3990099045/9014

NHRI > Institute of Biotechnology and Pharmaceutical Research > Jyh-Haur Chern > Patents > Item 3990099045/9014

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9014

Title:	抗腸病毒化合物
Other Titles:	Anti-enterovirus compounds
Authors:	Chern, JH;Shia, KS;Shih, SR;Hsu, TA;Tai, CL
Contributors:	Institute of Biotechnology and Pharmaceutical Research
Abstract:	本發明諸多特徵之一為式(A)之唑并嘧啶化合物： A為(CH2)q-CHRaRb；每一R1和R2可各自分別為氫、鹵素、氰基、硝基或烷基；或R1和R2共同成為(CH2)r；每一R3和R4可各自分別為氫、鹵素、氰基、硝基或烷基；每一R5、Ra和Rb可各自分別為芳基、芳烷基或雜芳基，並可選擇性地含有鹵素、氰基、硝基、烷基、芳基、芳烷基、雜芳基、OR、O(O)CR、C(O)R、C(O)OR、 C(O)NRR’、SR、S(O)R、S(O)OR、NRR’、NR(O)CR’、NRC(O)OR’或NRC(O)NR’R”之取代基；每一m、n、o、p和r可各自分別為0或1，及q為0、1或2；其中每一R、R’和R”可各自分別為氫或烷基，其限制條件為為m、n、o及p的總和需為1、2、3或4。This invention features, among others, a pyrazolopyrimidine compound of formula (A):A is (CH2)q-CHRaRb; each of R1 and R2, independently, is hydrogen, halogen, cyano, nitro, or alkyl; or R1 and R2 taken together is (CH2)r; each of R3 and R4, independently, is hydrogen, halogen, cyano, nitro, or alkyl; each of R5, Ra, and Rb, independently, is aryl, aralkyl, or heteroaryl, optionally substituted with halogen, cyano, nitro, alkyl, aryl, aralkyl, heteroaryl, OR, O(O)CR, C(O)R, C(O)OR, C(O)NRR’, SR, S(O)R, S(O)OR, NRR’, NR(O)CR’, NRC(O)OR’, or NRC(O)NR’R”; each of m, n, o, p, and r, independently, is 0 or 1, and q is 0, 1, or 2; in which each of R, R’, and R”, independently, is hydrogen or alkyl, provided that the sum of m, n, o, and p is 1, 2, 3, or 4.
Date:	2006-08-01
Relation:	I259083/2006-08-01
Link to:	https://twpat1.tipo.gov.tw/tipotwoc/tipotwkm?!!FR_I259083
Appears in Collections:	[Jyh-Haur Chern] Patents [Kak-Shan Shia] Patents [John Tsu-An Hsu] Patents

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