本發明是有關於一種藉由測定α－烯醇酶(alpha－enolase,ENO1)的含量來監測癌症發展的方法，其中α－烯醇酶的含量乃為癌症惡化的一個指標。在另一個實施例中，藉由測定血清中α－烯醇酶特異性抗體的含量，其中α－烯醇酶特異性抗體的含量乃為癌症存在和惡化的一個指標。此外，本發明亦提供一種藉由誘導抗－α－烯醇酶的免疫反應來抑制腫瘤生長的方法。The invention relates to a method of monitoring cancer development by examining the abundance of alpha－enolase protein wherein the abundance is an indication of the severity of cancer. In an alternative embodiment, the abundance of alpha－enolase specific antibodies is examined, wherein the abundance of the antibodies is an indication of the presence and severity of cancer. Also provided is a method of suppressing tumor growth by inducing the alpha－enolase specific antibodies immune response.
