國家衛生研究院 NHRI:Item 3990099045/9000
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    题名: Methods and compositions relating to COL2A1 gene mutations and osteonecrosis
    作者: Tsai, SF;Liu, YF;Chen, WM
    贡献者: Institute of Molecular and Genomic Medicine
    摘要: Methods, compounds, and kits for the diagnosis or screening of osteonecrosis are described, and the development of animal models for COL2A1 function in osteonecrosis is put forth. Novel mutations in the COL2A1 gene are identified that are associated with avascular necrosis of the femoral head. Methods of treatment of osteonecrosis and avascular necrosis of the femoral head, including gene therapy approaches comprising introduction of COL2A1 nucleic acid are contemplated.
    日期: 2010-05-18
    關聯: US7718366B2/2010-05-18
    Link to: http://v3.espacenet.com/publicationDetails/biblio?CC=US&NR=7718366&KC=B2
    显示于类别:[蔡世峯] 專利

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