國家衛生研究院 NHRI:Item 3990099045/8950

NHRI > Institute of Biomedical Engineering and Nanomedicine > Jen-Kun Chen > Patents > Item 3990099045/8950

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/8950

Title:	Radioactive gold nanoparticles and methods of making and using them
Authors:	Chen, JK;Peir, JJ;Wang, MY;Liu, CH;Chou, FI;Yang, CS;Yang, MH;Shih, MH
Contributors:	Institute of Biomedical Engineering and Nanomedicine
Abstract:	Methods of preparing a composition comprising non-ionic, radioactive gold nanoparticles (R-GNPs) are disclosed. The method comprises: a) providing an aqueous composition comprising gold (Au-197) ions in the absence of a template; and b) exposing the aqueous composition in the absence of the template to neutron irradiation to generate the composition comprising the non-ionic R-GNPs. Alternatively, the method comprises: a) providing an aqueous composition comprising gold (Au-197) nanoparticles (GNPs) in the absence of a template; and b) exposing the aqueous composition comprising the GNPs in the absence of the template to neutron irradiation and thereby generating the composition comprising the non-ionic R-GNPs. Compositions that comprises mesoporous silica nanoparticles (MSNs) and non-ionic R-GNPs encapsulated within pores and/or channels and further anchored to the surfaces of the MSNs, and methods of making the same are also disclosed.
Date:	2012-11-13
Relation:	US8309135B2/2012-11-13
Link to:	http://v3.espacenet.com/publicationDetails/biblio?CC=US&NR=8309135&KC=B2
Appears in Collections:	[Jen-Kun Chen] Patents [Chung-Shi Yang] Patents

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