本發明係提供由新穎寡核苷酸所成之組合物，及彼等用於偵測B型肝炎病毒(hepatitis B virus)之Pre-S區中是否有缺失突變的用途。此類缺失突變係與轉變成肝硬化或肝癌的危險性增加密切相關。This invention provides combinations of novel oligonucleotides and their use in detecting a deletion(s) in the Pre-S region of hepatitis B virus (HBV). Such a deletion(s) is associated with an increased risk of developing cirrhosis or hepatocellular carcinoma.
