國家衛生研究院 NHRI:Item 3990099045/8867
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    題名: Incidence and species distribution of candidaemia in Asia: A laboratory-based surveillance study
    作者: Tan, BH;Chakrabarti, A;Li, RY;Patel, AK;Watcharananan, SP;Liu, Z;Chindamporn, A;Tan, AL;Sun, PL;Wu, UI;Chen, YC
    貢獻者: Division of Infectious Diseases
    摘要: The epidemiology of candidaemia varies between hospitals and geographic regions. Although there are many studies from Asia, a large-scale cross-sectional study across Asia has not been performed. We conducted a 12-month, laboratory-based surveillance of candidaemia at 25 hospitals from China, Hong Kong, India, Singapore, Taiwan and Thailand. The incidence and species distribution of candidaemia were determined. There were 1,601 episodes of candidaemia among 1.2 million discharges. The overall incidence was 1.22 episodes per 1,000 discharges and varied among the hospitals (range, 0.16-4.53 per 1,000 discharges) and countries (range, 0.25-2.93 per 1,000 discharges). The number of Candida blood isolates and the total number of fungal isolates were highly correlated among the 6 countries (R²=0.87) and 25 hospitals (R²=0.77). There was a moderate correlation between incidence of candidaemia and the ICU/total bed ratio (R²=0.47), although ICUs contributed to only 23% of candidaemia cases. Of 1,910 blood isolates evaluated, C. albicans was most frequently isolated (41.3%), followed by C. tropicalis (25.4%), C. glabrata (13.9%) and C. parapsilosis (12.1%). The proportion of C. tropicalis among blood isolates was higher in haemato-oncology wards than others wards (33.7% vs 24.5%, p=0.0058) and was more likely to be isolated from tropical countries than other Asian countries (46.2% vs 18.9%, p=0.04). In conclusion, the ICU settings contribute, at least in part, to the incidence variation among hospitals. The species distribution is different from Western countries. Both geographic and healthcare factors contribute to the variation of species distribution.
    日期: 2015-10
    關聯: Clinical Microbiology and Infection. 2015 Oct;21(10):946-953.
    Link to: http://dx.doi.org/10.1016/j.cmi.2015.06.010
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1198-743X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000362924700013
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84942194042
    顯示於類別:[陳宜君] 期刊論文

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