國家衛生研究院 NHRI:Item 3990099045/8844
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    題名: In vitro dynamic fertilization by using EWOD device
    作者: Chung, LY;Shen, HH;Chung, YH;Chen, CC;Hsu, CH;Huang, HY;Yao, DJ
    貢獻者: Institute of Biomedical Engineering and Nanomedicine
    摘要: This research demonstrates the in vitro fertilization (IVF) technique by using the digital microfluidic (DMF) system. The DMF device has been proved with biocompatibility and used in this research for mouse gametes in vitro fertilization and embryos culture based on the dispersed droplet form. Dynamically moving, cell culture and observation can be achieved by the time-lapse microscopy in an incubator. The fertilization rate of IVF on DMF is 34.8%, and about 25% inseminated embryos dynamically cultured on DMF chip could develop into 8-cell stage. The result indicated that the DMF system has the potential used for assisted reproductive technology.
    日期: 2015-01
    關聯: 28th IEEE International Conference on Micro Electro Mechanical Systems. 2015 Jan;519-522.
    Link to: http://dx.doi.org/10.1109/MEMSYS.2015.7051006
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000370382900137
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84931034468
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