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    近3年内发表的文件:1(2.17%)
    含全文笔数:46(100.00%)

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    下载大于0次:46(100.00%)
    下载大于100次:46(100.00%)
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    最后更新时间: 2024-12-01 11:30


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    显示项目26-46 / 46. (共2页)
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    日期题名關聯
    2010-03-11 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313.
    2010-02-01 Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor ChemMedChem. 2010 Feb 1;5(2):255-267.
    2009-10 (1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055.
    2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.
    2009-07-23 Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233.
    2009-06 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.] European Journal of Medicinal Chemistry. 2009 Jun;44(6):2763-2763.
    2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622.
    2009-02-26 Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062.
    2008-12-25 Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167.
    2008-08 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.
    2008-03-01 Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold Bioorganic and Medicinal Chemistry Letters. 2008 Mar;18(5):1623-1627.
    2008 Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases Journal of Biomedicine and Biotechnology. 2008; 2008:Article number 841312.
    2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Journal of Medicinal Chemistry. 2006 Oct;49(21):6421-6424.
    2006-08-24 Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease Journal of Medicinal Chemistry. 2006 Aug;49(17):5154-5161.
    2006-06-15 Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies Journal of Medicinal Chemistry. 2006 Jun;49(12):3485-3495.
    2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712.
    2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Journal of Medicinal Chemistry. 2006 Feb;49(3):1212-1216.
    2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380.
    2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208.
    2005-12-15 The effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin Biochemical Journal. 2005 Dec;392(Pt. 3):545-554.
    2005-07-01 Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors Bioorganic and Medicinal Chemistry Letters. 2005 Jul;15(13):3271-3275.

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