English  |  正體中文  |  简体中文  |  Items with full text/Total items : 12145/12927 (94%)
Visitors : 854084      Online Users : 1460
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/8626


    Title: Fluoroquinolone prescribing in Taiwan, 2000 to 2010
    Authors: Kuo, SC;Shih, SM;Yang Lauderdale, TL;Chen, YC;Hsiung, CA
    Contributors: Division of Infectious Diseases;Division of Biostatistics and Bioinformatics
    Abstract: Purpose: The Taiwan Surveillance of Antimicrobial Resistance showed emergence and increasing fluoroquinolone (FQ) resistance in many important pathogens in Taiwan, including Escherichia coli, Streptococcus pneumoniae, Haemophilus influenzae, and other species, which may indicate common selective pressure exerted by increased antibiotic use. This study describes changes in FQ usage in Taiwan. Methods: This retrospective study determined the prescriptions of FQs from 2000 to 2010 using the sampling database from the National Health Insurance. Prescriptions of amoxicillin were used for comparison. Indications of prescriptions were based on International Classification of Diseases, Ninth Revision, Clinical Modification. The clinical characteristics of patients for whom FQs were prescribed were analyzed. IMS was used to estimate the amount of self-paid or inventory FQs. Results: Oral FQs in the outpatient department accounted for 84.6% of all FQs prescribed. Compared to oral amoxicillin, the prescription of oral FQs increased in recent years (odds ratio 1.089, 95% confidence interval 1.084-1.094). Non-US FDA indications accounted for 56.5% of all prescriptions. Respiratory tract, urinary tract, intra-abdominal and gastrointestinal infections accounted for 90% of approved indications. The specialties that most FQ prescribing occurred were otorhinolaryngology and family practice. Economic considerations, over the counter use, and treatment guideline recommendations are factors that cannot be included in this model and are our limitations. Conclusions: FQ resistance occurred concurrent to increased prescription of FQs. Restriction of oral FQ use may be necessary to halt this trend of drug resistance.
    Date: 2015-04
    Relation: Journal of Microbiology, Immunology and Infection. 2015 Apr;48(2, Suppl.1):S103.
    Link to: http://dx.doi.org/10.1016/j.jmii.2015.02.365
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1684-1182&DestApp=IC2JCR
    Appears in Collections:[陳宜君] 會議論文/會議摘要
    [楊采菱] 會議論文/會議摘要
    [郭書辰] 會議論文/會議摘要
    [熊昭] 會議論文/會議摘要

    Files in This Item:

    File Description SizeFormat
    SDO1684118215003989.pdf41KbAdobe PDF630View/Open


    All items in NHRI are protected by copyright, with all rights reserved.

    Related Items in TAIR

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback