國家衛生研究院 NHRI:
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    日期题名關聯
    2024-02-01 SARS-CoV-2 spike-FLIPr fusion protein plus lipidated FLIPr protects against various SARS-CoV-2 variants in hamsters Journal of Virology. 2024 Feb 20;98(2):Article number e0154623.
    2023-12 A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge Emerging Microbes and Infections. 2023 Dec;12(2):Article number 2272656.
    2020-05-09 Truncated pneumolysin from streptococcus pneumoniae as a TLR4-Antagonizing new drug for chronic inflammatory conditions Cells. 2020 May 9;9(5):Article number 1183.
    2019-10 Domain 4 of pneumolysin from Streptococcus pneumoniae is a multifunctional domain contributing TLR4 activating and hemolytic activity Biochemical and Biophysical Research Communications. 2019 Oct;517(4):596-602.
    2019-08-02 Delivery of antigen to CD8(+) dendritic cells by fusing antigen with formyl peptide receptor-like 1 inhibitor protein induces antitumor immunity Frontiers in Immunology. 2019 Aug 2;10:Article number 1839.
    2018-12-25 Identification of immunoreactive peptides of toxins to simultaneously assess the neutralization potency of antivenoms against neurotoxicity and cytotoxicity of naja atra venom Toxins. 2018 Dec 25;10(1):Article number 10.
    2018-12 A therapeutic vaccine targeting HPV E6/E7 with intrinsic Toll-like receptor 2 agonist activity induces antitumor immunity American Journal of Cancer Research. 2018 Dec;8(12):2528-2537.
    2018-04-23 Efficient uptake of recombinant lipidated survivin by antigen-presenting cells initiates antigen cross-presentation and antitumor immunity Frontiers in Immunology. 2018 Apr 23;9:Article number 822.
    2018-04-18 Polysorbasome: A colloidal vesicle contoured by polymeric bioresorbable amphiphiles as an immunogenic depot for vaccine delivery ACS Applied Materials and Interfaces. 2018 Apr 18;10(15):12553-12561.
    2016-11-09 Degradable emulsion as vaccine adjuvant reshapes antigen-specific immunity and thereby ameliorates vaccine efficacy Scientific Reports. 2016 Nov 09;6:Article number 36732.
    2016-07-29 Immunogenicity of a novel tetravalent vaccine formulation with four recombinant lipidated dengue envelope protein domain IIIs in mice Scientific Reports. 2016 Jul 29;6:Article number 30648.
    2016-07 The successful induction of T-cell and antibody responses by a recombinant measles virus-vectored tetravalent dengue vaccine provides partial protection against dengue-2 infection Human Vaccines and Immunotherapeutics. 2016 Jul;12(7):1678-1689.
    2016-05-06 A novel liposomal recombinant lipoimmunogen enhances anti-tumor immunity Journal of Controlled Release. 2016 May 6;233:57-63.
    2016-05 A toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population Oncotarget. 2016 May;7(21):30804-30819.
    2016-04 Carboxyl-terminal fusion of E7 into Flagellin shifts TLR5 activation to NLRC4/NAIP5 activation and induces TLR5-independent anti-tumor immunity Scientific Reports. 2016 Apr;6:Article number 24199.
    2016-03 S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex Nucleic Acids Research. 2016 Mar;44(5):2199-2213.
    2016-02 Recombinant lipidated dengue-3 envelope protein domain III stimulates broad immune responses in mice Vaccine. 2016 Feb;34(8):1054-1061.
    2015-12-29 The immunodominance change and protection of CD4+ T-cell responses elicited by an envelope protein domain III-based tetravalent dengue vaccine in mice PLoS ONE. 2015 Dec 29;10(12):Article number e0145717.
    2015-12 Recombinant bacterial lipoproteins as vaccine candidates Expert Review of Vaccines. 2015 Dec;14(12):1623-1632.
    2015-10 Gemcitabine enhances antitumor efficacy of recombinant lipoimmunogen-based immunotherapy OncoImmunology. 2015 Oct 29;5(3):e1095433.
    2015-08-13 Biochemical and immunological characterization of truncated fragments of the receptor-binding domains of C. difficile toxin A PLoS ONE. 2015 Aug 13;10(8):Article number e0135045.
    2015-08-07 Recombinant lipoprotein-based vaccine candidates against C. difficile infections Journal of Biomedical Science. 2015 Aug 7;22:Article number 65.
    2015-06 Recombinant lipoproteins as novel vaccines with intrinsic adjuvant Advances in Protein Chemistry and Structural Biology. 2015 Jun;99:55-74.
    2015-03 Self-adjuvanting lipoimmunogens for therapeutic HPV vaccine development: Potential clinical impact Expert Review of Vaccines. 2015 Mar;14(3):383-394.
    2014-05 Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells Journal of Immunology. 2014 May;192(9):4233-4241.
    2014-03-19 Toll-like receptor 9 agonist enhances anti-tumor immunity and inhibits tumor-associated immunosuppressive cells numbers in a mouse cervical cancer model following recombinant lipoprotein therapy Molecular Cancer. 2014 Mar 19;13:Article number 60.
    2014-03 Recombinant lipidated dengue-4 envelope protein domain III elicits protective immunity Vaccine. 2014 Mar;32(12):1346-1353.
    2014-03 A purified recombinant lipopeptide as adjuvant for cancer immunotherapy BioMed Research International. 2014 Mar;2014:Article number 349783.
    2014-01 A novel emulsion-type adjuvant containing CpG oligodeoxynucleotides enhances CD8+ T-cell-mediated anti-tumor immunity Journal of Controlled Release. 2014 Jan;173(1):158-165.
    2014-01 Disintegration and cancer immunotherapy efficacy of a squalane-in-water delivery system emulsified by bioresorbable poly(ethylene glycol)-block-polylactide Biomaterials. 2014 Jan;35(5):1686-1695.
    2013-09-19 Lipidated dengue-2 envelope protein domain III independently stimulates long-lasting neutralizing antibodies and reduces the risk of antibody-dependent enhancement PLoS Neglected Tropical Diseases. 2013 Sep 19;7(9):Article number e2432.
    2013-09 Induction of robust immunity by the emulsification of recombinant lipidated dengue-1 envelope protein domain III Microbes and Infection. 2013 Sep;15(10-11):719-728.
    2013-07 A consensus envelope protein domain III can induce neutralizing antibody responses against serotype 2 of dengue virus in non-human primates Archives of Virology. 2013 Jul;158(7):1523-1531.
    2012-07 Recombinant lipidated HPV E7 induces a Th-1-biased immune response and protective immunity against cervical cancer in a mouse model PLoS ONE. 2012 Jul;7(7):Article number e40970.
    2012-05 Dengue-1 envelope protein domain III along with PELC and CpG oligodeoxynucleotides synergistically enhances immune responses PLoS Neglected Tropical Diseases. 2012 May;6(5):Article number e1645.
    2012-02 Influence of medium components on the expression of recombinant lipoproteins in Escherichia coli Applied Microbiology and Biotechnology. 2012 Feb;93(4):1539-1552.
    2011-08 Presentation of lipopeptide by dendritic cells induces anti-tumor responses via an endocytosis-independent pathway in vivo Journal of Leukocyte Biology. 2011 Aug;90(2):323-332.
    2011-08 A novel single-dose dengue subunit vaccine induces memory immune responses PLoS ONE. 2011 Aug;6(8):Article number e23319.
    2011-07 Rapid Isolation and characterization of bacterial lipopeptides using liquid chromatography and mass spectrometry analysis Proteomics. 2011 Jul;11(13):2620-2627.
    2010-11 Biochemical characterizations of Escherichia coli-expressed protective antigen Ag473 of Neisseria meningitides group B Vaccine. 2010 Nov;28(51):8175-8182.
    2010-11 Generating stable chinese hamster ovary cell clones to produce a truncated SARS-CoV spike protein for vaccine development Biotechnology Progress. 2010 Nov;26(6):1733-1740.
    2010-09 Enhancement of specific cell-capture efficiency using a reversible dielectrophoresis field Sensors and Actuators, A: Physical. 2010 Sep;163(1):128-137
    2010-08 Emulsified nanoparticles containing inactivated influenza virus and CpG oligodeoxynucleotides critically influences the host immune responses in mice PLoS ONE. 2010 Aug;5(8):Article number e12279.
    2010-07 A recombinant lipoprotein containing an unsaturated fatty acid activates NF-kappaB through the TLR2 signaling pathway and induces a differential gene profile from a synthetic lipopeptide Molecular Immunology. 2010 Jul;47(11-12):2015-2021.
    2009-11-01 Identification of HLA-A11-restricted CTL epitopes derived from HPV type 18 using DNA immunization Cancer Biology and Therapy. 2009 Nov 1;8(21):2025-2032.
    2009-09-04 Immunogenic properties of RSV-B1 fusion (F) protein gene-encoding recombinant adenoviruses Vaccine. 2009 Sep 4;27(40):5460-5471.
    2009-08 Formulation and immunological evaluation of novel vaccine delivery systems based on bioresorbable poly(ethylene glycol)-block-poly(lactide-co-epsilon-caprolactone) Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2009 Aug;90(2):832-841.
    2009-08 Development of multi-phase emulsions based on bioresorbable polymers and oily adjuvant Pharmaceutical Research. 2009 Aug;26(8):1856-1862.
    2009-05-22 Immunological study of HA1 domain of hemagglutinin of influenza H5N1 virus Biochemical and Biophysical Research Communications. 2009 May 22;383(1):27-31.
    2009-05 Enhancement of potent antibody and T-cell responses by a single-dose, novel nanoemulsion-formulated pandemic influenza vaccine Microbes and Infection. 2009 May;11(6-7):654-660.

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