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感染症與疫苗研究所
冷治湘
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SARS-CoV-2 spike-FLIPr fusion prote...
A broad-spectrum pneumococcal vacci...
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Date
Title
Relation
2024-02-01
SARS-CoV-2 spike-FLIPr fusion protein plus lipidated FLIPr protects against various SARS-CoV-2 variants in hamsters
Journal of Virology. 2024 Feb 20;98(2):Article number e0154623.
2023-12
A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge
Emerging Microbes and Infections. 2023 Dec;12(2):Article number 2272656.
2020-05-09
Truncated pneumolysin from streptococcus pneumoniae as a TLR4-Antagonizing new drug for chronic inflammatory conditions
Cells. 2020 May 9;9(5):Article number 1183.
2019-10
Domain 4 of pneumolysin from Streptococcus pneumoniae is a multifunctional domain contributing TLR4 activating and hemolytic activity
Biochemical and Biophysical Research Communications. 2019 Oct;517(4):596-602.
2019-08-02
Delivery of antigen to CD8(+) dendritic cells by fusing antigen with formyl peptide receptor-like 1 inhibitor protein induces antitumor immunity
Frontiers in Immunology. 2019 Aug 2;10:Article number 1839.
2018-12-25
Identification of immunoreactive peptides of toxins to simultaneously assess the neutralization potency of antivenoms against neurotoxicity and cytotoxicity of naja atra venom
Toxins. 2018 Dec 25;10(1):Article number 10.
2018-12
A therapeutic vaccine targeting HPV E6/E7 with intrinsic Toll-like receptor 2 agonist activity induces antitumor immunity
American Journal of Cancer Research. 2018 Dec;8(12):2528-2537.
2018-04-23
Efficient uptake of recombinant lipidated survivin by antigen-presenting cells initiates antigen cross-presentation and antitumor immunity
Frontiers in Immunology. 2018 Apr 23;9:Article number 822.
2018-04-18
Polysorbasome: A colloidal vesicle contoured by polymeric bioresorbable amphiphiles as an immunogenic depot for vaccine delivery
ACS Applied Materials and Interfaces. 2018 Apr 18;10(15):12553-12561.
2016-11-09
Degradable emulsion as vaccine adjuvant reshapes antigen-specific immunity and thereby ameliorates vaccine efficacy
Scientific Reports. 2016 Nov 09;6:Article number 36732.
2016-07-29
Immunogenicity of a novel tetravalent vaccine formulation with four recombinant lipidated dengue envelope protein domain IIIs in mice
Scientific Reports. 2016 Jul 29;6:Article number 30648.
2016-07
The successful induction of T-cell and antibody responses by a recombinant measles virus-vectored tetravalent dengue vaccine provides partial protection against dengue-2 infection
Human Vaccines and Immunotherapeutics. 2016 Jul;12(7):1678-1689.
2016-05-06
A novel liposomal recombinant lipoimmunogen enhances anti-tumor immunity
Journal of Controlled Release. 2016 May 6;233:57-63.
2016-05
A toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population
Oncotarget. 2016 May;7(21):30804-30819.
2016-04
Carboxyl-terminal fusion of E7 into Flagellin shifts TLR5 activation to NLRC4/NAIP5 activation and induces TLR5-independent anti-tumor immunity
Scientific Reports. 2016 Apr;6:Article number 24199.
2016-03
S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex
Nucleic Acids Research. 2016 Mar;44(5):2199-2213.
2016-02
Recombinant lipidated dengue-3 envelope protein domain III stimulates broad immune responses in mice
Vaccine. 2016 Feb;34(8):1054-1061.
2015-12-29
The immunodominance change and protection of CD4+ T-cell responses elicited by an envelope protein domain III-based tetravalent dengue vaccine in mice
PLoS ONE. 2015 Dec 29;10(12):Article number e0145717.
2015-12
Recombinant bacterial lipoproteins as vaccine candidates
Expert Review of Vaccines. 2015 Dec;14(12):1623-1632.
2015-10
Gemcitabine enhances antitumor efficacy of recombinant lipoimmunogen-based immunotherapy
OncoImmunology. 2015 Oct 29;5(3):e1095433.
2015-08-13
Biochemical and immunological characterization of truncated fragments of the receptor-binding domains of C. difficile toxin A
PLoS ONE. 2015 Aug 13;10(8):Article number e0135045.
2015-08-07
Recombinant lipoprotein-based vaccine candidates against C. difficile infections
Journal of Biomedical Science. 2015 Aug 7;22:Article number 65.
2015-06
Recombinant lipoproteins as novel vaccines with intrinsic adjuvant
Advances in Protein Chemistry and Structural Biology. 2015 Jun;99:55-74.
2015-03
Self-adjuvanting lipoimmunogens for therapeutic HPV vaccine development: Potential clinical impact
Expert Review of Vaccines. 2015 Mar;14(3):383-394.
2014-05
Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells
Journal of Immunology. 2014 May;192(9):4233-4241.
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