In this paper, a novel design for a perfusion-based sensing probe that performs in situ protein detection with sensor surface regeneration was reported. By using gold nanoparticles to enhance the immune conjugation signal and by choosing an UV-switchable o-NBA solution as an elution buffer, repeated detection using a single sensing probe can be achieved.
Date:
2009-11
Relation:
13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009. 2009 Nov:942-944.
