國家衛生研究院 NHRI:Item 3990099045/8117

NHRI > Institute of Biomedical Engineering and Nanomedicine > Chung-Shi Yang > Conference Papers/Meeting Abstract > Item 3990099045/8117

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Title:	Rapid and high efficient bio-molecule separation by nano elecctrostatic sieving
Authors:	Wu, RG;Wu, YS;Yang, CS;Tseng, FG
Contributors:	Center for Nanomedicine Research
Abstract:	In this research, we demonstrate a rapid size exclusion and nano electrostaticsieving method for biomolecules separation by charged and sized with a wellaligned multiwall carbon nanotubes (MWCNTs) array as an ordered nanoporous medium in a microfluidic chip. To manipulate solution ionic strength in this nanostructure, MWCNTs was modified with negative charged functional group by surface plasma treatment. Both size and charge sieving of biomolecules were observed attributing to high efficient separation. Rapid separation of three short dsDNA has been achieved in 1 min. In addition, a great reduction of band broadening for sample trapped was obtained when proteins was separated by the well-aligned MWCNTs array.
Date:	2009-11
Relation:	13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009. 2009 Nov:803-805.
Link to:	http://www.geni-pco.com/mtas2009/
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84901814672
Appears in Collections:	[Chung-Shi Yang] Conference Papers/Meeting Abstract

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