國家衛生研究院 NHRI:Item 3990099045/8082
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/8082


    Title: Directly thiolated modification onto the surface of detonation nanodiamonds
    Authors: Hsu, MH;Chuang, H;Cheng, FY;Huang, YP;Han, CC;Chen, JY;Huang, SC;Chen, JK;Wu, DS;Chu, HL;Chang, CC
    Contributors: Center for Nanomedicine Research
    Abstract: An efficient method for modifying the surface of detonation nanodiamonds (5 and 100 nm) with thiol groups (-SH) by using an organic chemistry strategy is presented herein. Thiolated nanodiamonds were characterized by spectroscopic techniques, and the atomic percentage of sulfur was analyzed by elemental analysis and X-ray photoelectron spectroscopy. The conjugation between thiolated nanodiamonds and gold nanoparticles was elucidated by transmission electron microscopy and UV-vis spectrometry. Moreover, the material did not show significant cytotoxicity to the human lung carcinoma cell line and may prospectively be applied in bioconjugated technology. The new method that we elucidated may significantly improve the approach to surface modification of detonation nanodiamonds and build up a new platform for the application of nanodiamonds.
    Date: 2014-05
    Relation: ACS Applied Materials and Interfaces. 2014 May;6(10):7198-7203.
    Link to: http://dx.doi.org/10.1021/am500324z
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1944-8244&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000336639200028
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84901650471
    Appears in Collections:[Jen-Kun Chen] Periodical Articles

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