國家衛生研究院 NHRI:Item 3990099045/8052
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    题名: Yeast oropharyngeal colonization in human immunodeficiency virus-infected patients in central Taiwan
    作者: Ho, MW;Yang, YL;Lin, CC;Chi, CY;Chen, HT;Lin, PC;Hsieh, LY;Chou, CH;Chu, WL;Wu, CP;Lauderdale, TL;Lo, HJ
    贡献者: Division of Infectious Diseases
    摘要: A prospective, cross-sectional study was conducted at a medical center in central Taiwan to understand the prevalence, associated factors, and microbiologic features for oropharyngeal yeast colonization in human immunodeficiency virus-infected outpatients. Oral yeast colonization was detected in 127 (45 %) patients, including 21 (16.5 %) colonized by more than one species. Of the 154 isolates, Candida albicans was the most common species (114, 74 %), followed by Candida dubliniensis (10, 6.5 %), Candida glabrata (10, 6.5 %), Candida tropicalis (7, 4.5 %), and 13 others. We found that receiving antituberculous drug (p = 0.046) or atazanavir (p = 0.045) was two predictors for patients colonized by non-C. albicans species (p = 0.005) and risking mixed yeast colonization (p = 0.009). Even though our data showed that clinical antifungal drugs remained effective in vitro against the colonizing yeasts, the increased mixed yeast colonization indicates a potential issue for controlling mixed infections in hospital settings.
    日期: 2014-06
    關聯: Mycopathologia. 2014 Jun;177(5-6):309-317.
    Link to: http://dx.doi.org/10.1007/s11046-014-9753-5
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0301-486X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000336379200009
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84901020018
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