國家衛生研究院 NHRI:
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    近3年内发表的文件:13(9.15%)
    含全文笔数:142(100.00%)

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    最后更新时间: 2024-12-04 03:52


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    显示项目126-142 / 142. (共6页)
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    日期题名關聯
    2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380.
    2006-01-01 Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system Bioorganic and Medicinal Chemistry. 2006 Jan 1;14(1):83-91.
    2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208.
    2005-05 Shear stress inhibits smooth muscle cell-induced inflammatory gene expression in endothelial cells - Role of NF-kappa B Arteriosclerosis, Thrombosis, and Vascular Biology. 2005 May;25(5):963-969.
    2005-05 Pharmaceutical design of antimitotic agents based on combretastatins Current Pharmaceutical Design. 2005 May;11(13):1655-1677.
    2005 Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3 '- digallate (TF3) Evidence-based Complementary and Alternative Medicine. 2005;2:209-215.
    2004-09-10 Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV FEBS Letters. 2004 Sep;574(1-3):116-120.
    2004-08-12 Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents Journal of Medicinal Chemistry. 2004 Aug;47(17):4247-4257.
    2004-07-15 A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells Biochemical Pharmacology. 2004 Jul;68(2):293-303.
    2004-07-01 BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo Cancer Research. 2004 Jul;64(13):4621-4628.
    2004-07 Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide Antimicrobial Agents and Chemotherapy. 2004 Jul;48(7):2693-2696.
    2004-05-20 Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents Journal of Medicinal Chemistry. 2004 May;47(11):2897-2905.
    2003-12-01 Substituent effects on di-pi-methane and aza-di-pi-methane rearrangements of dibenzo[f,h]quinoxalinobarrelenes Tetrahedron Letters. 2003 Dec;44(49):8761-8764.
    2003-06-15 Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent Biochemical Pharmacology. 2003 Jun;65(12):2009-2019.
    2003-03-10 Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents (vol 13, pg 101, 2003) Bioorganic and Medicinal Chemistry Letters. 2003 Mar;13(5):977-977.
    2003-01-06 Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents Bioorganic and Medicinal Chemistry Letters. 2003 Jan;13(1):101-105.
    2002-06-06 Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents Journal of Medicinal Chemistry. 2002 Jun;45(12):2556-2562.

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