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2006-01-12
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380.
2006-01-01
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system
Bioorganic and Medicinal Chemistry. 2006 Jan 1;14(1):83-91.
2005-12-29
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities
Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208.
2005-05
Shear stress inhibits smooth muscle cell-induced inflammatory gene expression in endothelial cells - Role of NF-kappa B
Arteriosclerosis, Thrombosis, and Vascular Biology. 2005 May;25(5):963-969.
2005-05
Pharmaceutical design of antimitotic agents based on combretastatins
Current Pharmaceutical Design. 2005 May;11(13):1655-1677.
2005
Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3 '- digallate (TF3)
Evidence-based Complementary and Alternative Medicine. 2005;2:209-215.
2004-09-10
Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV
FEBS Letters. 2004 Sep;574(1-3):116-120.
2004-08-12
Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents
Journal of Medicinal Chemistry. 2004 Aug;47(17):4247-4257.
2004-07-15
A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells
Biochemical Pharmacology. 2004 Jul;68(2):293-303.
2004-07-01
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo
Cancer Research. 2004 Jul;64(13):4621-4628.
2004-07
Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide
Antimicrobial Agents and Chemotherapy. 2004 Jul;48(7):2693-2696.
2004-05-20
Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents
Journal of Medicinal Chemistry. 2004 May;47(11):2897-2905.
2003-12-01
Substituent effects on di-pi-methane and aza-di-pi-methane rearrangements of dibenzo[f,h]quinoxalinobarrelenes
Tetrahedron Letters. 2003 Dec;44(49):8761-8764.
2003-06-15
Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent
Biochemical Pharmacology. 2003 Jun;65(12):2009-2019.
2003-03-10
Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents (vol 13, pg 101, 2003)
Bioorganic and Medicinal Chemistry Letters. 2003 Mar;13(5):977-977.
2003-01-06
Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents
Bioorganic and Medicinal Chemistry Letters. 2003 Jan;13(1):101-105.
2002-06-06
Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents
Journal of Medicinal Chemistry. 2002 Jun;45(12):2556-2562.
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