國家衛生研究院 NHRI:Item 3990099045/7763
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    题名: Drug delivery system design and development for boron neutron capture therapy on cancer treatment
    作者: Huang, SLC;Hsieh, WY;Chen, JY;Huang, SC;Chen, JK;Hsu, MH
    贡献者: Center for Nanomedicine Research
    摘要: We have already synthesized a boron-containing polymeric micellar drug delivery system for boron neutron capture therapy (BNCT). The synthesized diblock copolymer, boron-terminated copolymers (Bpin-PLA-PEOz), consisted of biodegradable poly(D,l-lactide) (PLA) block and water-soluble polyelectrolyte poly(2-ethyl-2-oxazoline) (PEOz) block, and a cap of pinacol boronate ester (Bpin). In this study, we have demonstrated that synthesized Bpin-PLA-PEOz micelle has great potential to be boron drug delivery system with preliminary evaluation of biocompatibility and boron content.
    日期: 2014-06
    關聯: Applied Radiation and Isotopes. 2014 Jun;88:89-93.
    Link to: http://dx.doi.org/10.1016/j.apradiso.2013.12.025
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0969-8043&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000338606100021
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84901857533
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