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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/7726


    Title: Six-month follow-up study of health markers of nanomaterials among workers handling engineered nanomaterials
    Authors: Liao, HY;Chung, YT;Lai, CH;Wang, SL;Chiang, HC;Li, LA;Tsou, TC;Li, WF;Lee, HL;Wu, WT;Lin, MH;Hsu, JH;Ho, JJ;Chen, CJ;Shih, TS;Lin, CC;Liou, SH
    Contributors: Division of Environmental Health and Occupational Medicine
    Abstract: Abstract The aim of this study was to identify the health hazards and possible exposure surveillance markers of workers exposed to nanoparticles during manufacturing and application in comparison to a group of unexposed workers. For this longitudinal study, we recruited 158 nanomaterial-handling workers and 104 non-exposed workers from 14 manufacturing plants in Taiwan (baseline). Among them, 124 nanomaterial-handling workers and 77 unexposed workers were monitored 6 months later. We investigated pulmonary and cardiovascular disease markers, inflammation and oxidative stress markers, antioxidant enzymes and genotoxicity markers. Antioxidant enzymes (superoxide dismutase, glutathione peroxidase) and cardiovascular markers (vascular cell adhesion molecule, paraoxonase) were significantly associated with nanomaterial-handling during the 6-month follow-up period. In addition, the small airway damage marker (Clara cell protein 16) and lung function test parameters were also significantly associated with handling nanomaterials. The study markers and lung function tests are possible markers that could be useful for surveillance of nanomaterial-handling workers.
    Date: 2014-08
    Relation: Nanotoxicology. 2014 Aug;8(S1):100-110.
    Link to: http://dx.doi.org/10.3109/17435390.2013.858793
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1743-5390&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000340524300010
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?eid=2-s2.0-84905981805partnerID=40
    Appears in Collections:[劉紹興] 期刊論文
    [李婉芬(2001-2009)] 期刊論文
    [鄒粹軍] 期刊論文
    [李立安] 期刊論文
    [王淑麗] 期刊論文
    [江宏哲] 期刊論文
    [吳威德] 期刊論文

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