In this paper, we present a microfluidic device that allows for sorting of cancer cells based on their chemotactic migration speeds. We used breast cancer cell line cells to demonstrate cell seeding, migration and releasing in our microfluidic device. The ability of our device to provide subpopulations of chemotactically heterogeneous cancer cells should find useful applications in studying cancer and metastasis.
Date:
2011-10
Relation:
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences. 2011 Oct;3:1701-1703.