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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/7508


    Title: Synthesis and biological evaluation of novel C-aryl d-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitors
    Authors: Lin, TS;Liw, YW;Song, JS;Hsieh, TC;Yeh, HW;Hsu, LC;Lin, CJ;Wu, SH;Liang, PH
    Contributors: Institute of Biotechnology and Pharmaceutical Research
    Abstract: Novel C-aryl-d-glucofuranosides were synthesized and evaluated for their capacity to inhibit human sodium-dependent glucose co-transporter 2 (hSGLT2) and hSGLT1. Compound 21q demonstrated the best in vitro inhibitory activity against SGLT2 in this series (EC50 = 0.62 μM).
    Date: 2013-11
    Relation: Bioorganic and Medicinal Chemistry. 2013 Nov;21(21):6282-6291.
    Link to: http://dx.doi.org/10.1016/j.bmc.2013.08.067
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0968-0896&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000325164500003
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84885177187
    Appears in Collections:[其他] 期刊論文

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