國家衛生研究院 NHRI:Item 3990099045/7378
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/7378


    Title: Newly diagnosed major depressive disorder and the risk of erectile dysfunction: A population-based cohort study in Taiwan
    Authors: Huang, SS;Lin, CH;Chan, CH;Loh, EW;Lan, TH
    Contributors: Center for Neuropsychiatric Research
    Abstract: AbstractIntroduction The primary aim of this study was to explore the incidence rate of erectile dysfunction (ED) among major depressive disorder (MDD) patients in an Asian country. The second aim was to compare the risk of ED in MDD patients that were treated using antidepressants with a high risk-ED, antidepressants with a low risk-ED, or without treatment. Methods We identified 4339 male patients with newly diagnosed MDD using the National Health Database. Four matched controls per case were selected for the study. Results The mean age of the participants was 42.3±16.9. A higher crude HR of 3.6 (95% CI: 2.8–4.6) was seen in the male patients with MDD. After adjusting for obesity, monthly income, urbanization level, and comorbidity, the MDD patients had a 3.2-fold higher HR for an ED diagnosis than the controls. Patients with untreated depression had the highest risk of ED, compared to the control group (HR=3.9). Patients treated with IHiRA had a medium risk of developing ED (HR=3.6), and patients treated with ILoRA had the lowest risk of ED (HR: 2.5). Conclusion This prospective cohort study found an association between ED and prior MDD. Patients with untreated depression may have the highest risk of developing ED.
    Date: 2013-12
    Relation: Psychiatry Research. 2013 Dec;210(2):601-606.
    Link to: http://dx.doi.org/10.1016/j.psychres.2013.06.012
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0165-1781&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000328518600037
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84886952793
    Appears in Collections:[Others] Periodical Articles

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