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    日期題名關聯
    2018-04 4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy Bioorganic Chemistry. 2018 Apr;77:600-607.
    2017-12 Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells Free Radical Biology and Medicine. 2017 Dec;113:505-518.
    2017-08 Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness Cancer Research. 2017 Aug;77(16):4305-4316.
    2017-07 Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors Journal of Biomolecular Structure and Dynamics. 2017 Jun;35(8):1833-1848.
    2017-07 Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors Journal of Medicinal Chemistry. 2017 Jul;60(13):5599-5612.
    2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Oncotarget. 2016 Dec;7(52):86239-86256.
    2016-12 Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy European Journal of Cancer. 2016 Dec;68(Suppl. 1):S83-S84.
    2016-08 Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo Oncotarget. 2016 Aug;7(31):49310-49321.
    2016-07-01 MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma PLoS ONE. 2016 Jul 1;11(7):Article number e0158440.
    2016-01 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.
    2016-01 Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy Journal of Medicinal Chemistry. 2016 Jan;59(1):419-430.
    2015-12 Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model European Journal of Medicinal Chemistry. 2015 Dec;106:60-74.
    2015-09 O6-Methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma International Journal of Cancer. 2015 Sep;137(6):1291-1305.
    2015-08 Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes Bioorganic and Medicinal Chemistry. 2015 Aug;23(15):4230-4236.
    2015-08 Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692.
    2015-08 Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 180.
    2015-05 Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo Biochemical Pharmacology. 2015 May;95(1):28-37.
    2015-05 Enhanced antitumor activity of rapamycin and genipin, a UCP-2 inhibitor, in lung cancer Journal of Clinical Oncology. 2015 May;33(15, Suppl.):e13595.
    2015-01 Two new labdane-type diterpene acids from the wood of cunninghamia konishii Helvetica Chimica Acta. 2015 Jan;98(1):123-127.
    2014-11 Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93.
    2014-11 Cytokine induces MIR-424 expression and modulates SOCS2/STAT5 signaling pathway in oral cancer European Journal of Cancer. 2014 Nov;50(Suppl. 6):147.
    2014-10 Copper-chelator exerts synergistic interaction with platinum drugs through modulating copper transporters in oxaliplatin-resistant human gastric cancer cell Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 3753.
    2014-05 Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells Journal of Medicinal Chemistry. 2014 May;57(10):4009-4022.
    2014-05 High expression of Hsp90-beta and GRP 94 association with poor survival in resected non-small cell lung cancer patients Journal of Clinical Oncology. 2014 May;32(15, Suppl.):e13522.
    2014-04 Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones European Journal of Medicinal Chemistry. 2014 Apr 22;77(2):306-314.

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