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日期	題名	關聯
2024-11-08	Endosomes serve as signaling platforms for RIG-I ubiquitination and activation	Science Advances. 2024 Nov 08;10(45):Article number eadq0660.
2024-06-14	DUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling	Cell Death Discovery. 2024 Jun 14;10:Article number 285.
2024-06	UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis	Journal of Autoimmunity. 2024 Jun;146:Article number 103221.
2024-03-27	Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck	Journal of Biomedical Science. 2024 Mar 27;31:Article number 33.
2024-01-15	The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling	Nature Communications. 2024 Jan 15;15:Article number 532.
2023-12-05	Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice	International Journal of Molecular Sciences. 2023 Dec 05;24(24):Article number 17136.
2023-11-01	DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha	Journal of Clinical Investigation. 2023 Nov 01;133(21):Article number e166269.
2023-08-22	ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification	Journal of Biomedical Science. 2023 Aug 22;30:Article number 71.
2023-06	Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia	Journal of Clinical Investigation. 2023 Jun 15;133(12):Article number e163873.
2023-04-22	DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia	International Journal of Molecular Sciences. 2023 Apr 22;24(9):Article number 7690.
2023-02-10	Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis	BMC Medicine. 2023 Feb 10;21:Article number 46.
2022-07-27	SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19	EMBO Molecular Medicine. 2022 Jul 27:Article number e15904.
2022-07-18	MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation	Theranostics. 2022 Jul 18;12(12):5744-5760.
2022-06-15	DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction	Journal of Biomedical Science. 2022 Jun 15;29:Article number 40.
2022-02-18	Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice	iScience. 2022 Feb 18;25(2):Article number 103738.
2022-02	Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus	Annals of the Rheumatic Diseases. 2022 Feb;81(2):243-254.
2022-01	Induction of interferon-gamma and tissue inflammation by overexpression of eosinophil cationic protein in T cells and exosomes	Arthritis and Rheumatology. 2022 Jan;74(1):92-104.
2021-11-23	Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice	Cell Reports. 2021 Nov 23;37(8):Article number 110016.
2021-10-25	BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus	Theranostics. 2021 Oct 25;11(20):9953-9966.
2020-10-12	Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases	International Journal of Molecular Sciences. 2020 Oct 12;21(20):Article number 7515.
2020-08-12	DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1	Journal of Immunology. 2020 Aug 12;205(6):1644-1652.
2019-12	DUSP22 suppresses prostate cancer proliferation by targeting the EGFR-AR axis	FASEB Journal. 2019 Dec 5;33(12):14653-14667.
2019-11-13	MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus	Cells. 2019 Nov 13;8(11):Article number 1433.
2019-10-22	MAP4K3/GLK in autoimmune disease, cancer and aging	Journal of Biomedical Science. 2019 Oct 22;26:Article number 82.
2019-10	AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus	FASEB Journal. 2019 Oct;3(10):11469-11480.
2019-10	MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1	Cancer Research. 2019 Oct;79(19):4978-4993.
2019-07	PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency	Cell Death and Differentiation. 2019 Jul;26 (7):1221-1234.
2019-05-30	Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability	International Journal of Molecular Sciences. 2019 May 30;20(11):Article number 2668.
2019-04	MAP4K4 inhibition promotes survival of human stem cell-derived cardiomyocytes and reduces infarct size in vivo	Cell Stem Cell. 2019 Apr;24(4):579-591.e12.
2018-12	RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell	Biochimica et Biophysica Acta-Molecular Cell Research. 2018 Feb;1865(2):259-272.
2018-12	Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation	FASEB Journal. 2018 Dec;32(12):6760-6770.
2018-09-12	GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease	Science Advances. 2018 Sep 12;4(9):Article number eaat5401.
2018-09-06	RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis	International Journal of Molecular Sciences. 2018 Sep 6;19(9):Article number 2646.
2018-08-21	DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation	Proceedings of the National Academy of Sciences of the United States of America. 2018 Aug 21;115(34):E8027-E8036.
2017-11	Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration	Oncogene. 2017 Nov;36(47):6509-6517.
2017-02	Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice	Nature Microbiology. 2017 Feb;2(2):Article number 16220.
2017-01-07	MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes	Journal of Biomedical Science. 2017 Jan 7;24:Article number 4.
2016-08	Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis	Oncotarget. 2016 Aug;7(36):57593-57605.
2016-07	GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer	Oncotarget. 2016 Jul;7(27):41748-41757.
2016-07	Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase	Oncotarget. 2016 Jul;7(31):49765-49776.
2016-03-08	Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients	Oncotarget. 2016 Mar 8;7(10):10976-10989.
2016-01	MAP4K family kinases in immunity and inflammation	Advances in Immunology. 2016 Jan;129:277-314.
2016-01	TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity	Cellular Signalling. 2016 Jan;28(1):145-151.
2014-09-12	PP4 is essential for germinal center formation and class switch recombination in mice	PLoS ONE. 2014 Sep 12;9(9):Article number e107505.
2014-08-06	HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance	Nature Communications. 2014 Aug 6;5:Article number 4602.
2014-05-07	Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity	Cell and Bioscience. 2014 May 7;4:Article number 25.
2014-04-09	The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck	Nature Communications. 2014 Apr 9;5:Article number 3618.
2014-02-15	Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation	Journal of Immunology. 2014 Feb 15;192(4):1547-1557.
2014-02	The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1	Journal of Biological Chemistry. 2014 Feb 14;289(7):4009-4017.
2013-10	Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis	Arthritis and Rheumatism. 2013 Oct;65(10):2573-2582.

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