國家衛生研究院 NHRI:Item 3990099045/6744
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    题名: Complexity of Beta-lactamases among clinical Aeromonas isolates and its clinical implications
    其它题名: Complexity of β-lactamases among clinical Aeromonas isolates and its clinical implications
    作者: Chen, PL;Ko, WC;Wu, CJ
    贡献者: Division of Infectious Diseases
    摘要: Aeromonas species, aquatic Gram-negative bacilli, distributed globally and ubiquitously in the natural environment, may be implicated in a variety of human diseases. They can produce various b -lactamases which confer resistance to a broad spectrum of b -lactams, and therefore in vitro susceptibility testing must be used to guide antimicrobial therapy. However, conven-tional in vitro susceptibility tests may sometimes fail to detect these b -lactamases, and hence raise a therapeutic challenge. In this review article, two chromosomally mediated b -lacta-mases (i.e., AmpC b -lactamases and metallo- b -lactamases) and acquired extended-spectrum b -lactamases in aeromonads are reviewed, and the clinical implications of the complexity of b -lactamases are discussed.
    日期: 2012-12
    關聯: Journal of Microbiology, Immunology and Infection. 2012 Dec;45(6):398-403.
    Link to: http://dx.doi.org/10.1016/j.jmii.2012.08.008
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1684-1182&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000313092400002
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84870291269
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