國家衛生研究院 NHRI:Item 3990099045/6733
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/6733


    Title: Sarcopenia is related to increased risk for low bone mineral density
    Authors: Wu, CH;Yang, KC;Chang, HH;Yen, JF;Tsai, KS;Huang, KC
    Contributors: Division of Geriatric Research
    Abstract: Lean body mass is positively correlated with bone mineral density (BMD). The association between sarcopenia and BMD is less studied. The aim of the study is to investigate the association between sarcopenia and abnormal BMD. A total of 600 community residents aged 40-85yr (mean=63.63?10.12) from Taipei, Taiwan were included. Abnormal and normal BMD groups were categorized by T-score of femoral neck and lumbar spine (L2-L4) measured by dual-energy X-ray absorptiometry. Skeletal muscle mass (SM) index (SMI) was obtained from SM divided by height squared using bioelectrical impedance analysis (BIA) method. Sarcopenia was defined as SMI less than 8.87kg/m(2) in men and 6.42kg/m(2) in women according to previous Taiwanese sarcopenia study. The association between BMD groups and sarcopenia was examined using binary logistic regression analyses after controlling potential confounders. Subjects with sarcopenia were at higher risk for low BMD (odds ratio (OR) = 1.59, 95% confidence interval (CI)=1.06-2.39 for femoral neck BMD and OR=1.72, 95% CI=1.09-2.72 for lumbar BMD) compared with the nonsarcopenia group. Even in different gender groups with age categorized, sarcopenia was still an important independent factor in female group. The least square (LS) means of BMD of femoral neck and lumbar spine were significantly lower in sarcopenia group. The risk of low BMD increased significantly with sarcopenia.
    Date: 2013-01
    Relation: Journal of Clinical Densitometry. 2013 Jan;16(1):98-103.
    Link to: http://dx.doi.org/10.1016/j.jocd.2012.07.010
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1094-6950&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000315178500021
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84873133662
    Appears in Collections:[Kuo-Chin Huang] Periodical Articles

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