國家衛生研究院 NHRI:Item 3990099045/6732

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Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/6732

Title:	An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold
Authors:	Shiao, HY;Kuo, CC;Horng, JT;Shih, SR;Chang, SY;Liao, CC;Hsu, JTA;Kumar, AP;Chao, YS;Hsieh, HP
Contributors:	Institute of Biotechnology and Pharmaceutical Research;National Institute of Cancer Research
Abstract:	An efficient, mild and scalable synthesis of angelicin scaffold based compounds was developed. Particularly, the new synthetic route described here circumvents the need for the previously reported key Fries rearrangement step, which uses impractically harsh conditions. The new methodology is applied to the synthesis of several, previously reported analogs of angelicin which have potent anti-influenza and anti-cancer activities.
Date:	2012-12
Relation:	Journal of the Chinese Chemical Society. 2012 Dec;59(12):1548-1554.
Link to:	http://dx.doi.org/10.1002/jccs.201200233
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0009-4536&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000311592100010
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84872862978
Appears in Collections:	[Hsing-Pang Hsieh] Periodical Articles [John Tsu-An Hsu] Periodical Articles [Yu-Sheng Chao(2002-2013)] Periodical Articles [Ching-Chuan Kuo] Periodical Articles

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