國家衛生研究院 NHRI:Item 3990099045/6729
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    题名: Effects of dipeptidyl peptidase 4 inhibition with MK-0431 on syngeneic mouse islet transplantation
    作者: Juang, JH;Kuo, CH;Liu, YH;Chen, CT
    贡献者: Institute of Biotechnology and Pharmaceutical Research
    摘要: Dipeptidyl peptidase-4 (DPP-4) inhibitors increase circulating levels of active incretin hormones-glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) by blocking their degradation. In addition to their insulinotropic actions, GLP-1 and GIP also promote beta-cell proliferation and survival. The aim of this study was to test if DPP-4 inhibition with MK-0431 is beneficial for diabetic recipients with a marginal number of fresh islets.
    日期: 2011-09
    關聯: Diabetologia. 2011 Sep;54(Suppl. 1):S181.
    Link to: http://dx.doi.org/10.1007/s00125-011-2276-4
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0012-186X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000307671301084
    显示于类别:[陳炯東] 會議論文/會議摘要

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