國家衛生研究院 NHRI:Item 3990099045/6725
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    题名: Risk factors for Salmonella gastroenteritis in children less than five years of age in Taiwan
    作者: Chen, CJ;Wu, FT;Hsiung, CA;Chang, WC;Wu, HS;Wu, CY;Lin, JS;Huang, FC;Huang, YC
    贡献者: Division of Biostatistics and Bioinformatics
    摘要: BACKGROUND: Nontyphoid Salmonella spp. have been among the most common pathogens of acute gastroenteritis in children in Taiwan. However, the principal sources of transmission remain poorly defined. METHODS: A matched case-control study was conducted from January 2009 to October 2010. Cases were children aged 2 to 60 months who were hospitalized at three medical centers in Taiwan because of diarrhea and found to have culture-proven nontyphoidal Salmonella infection. Controls were healthy children or children with acute diseases other than gastroenteritis and matched to cases by age, gender, study site, and enrollment date. RESULTS: A total of 396 cases and 930 matched controls were included for analysis. Multivariate analysis using conditional logistic regression identified contact with household members having diarrhea (matched odds ratio [mOR], 17.9; 95% confidence interval [CI], 8.82-36.34; P < .0001), consumption of instant powdered milk (mOR, 2.04; 95% CI, 1.05-3.94; P = .0344), visits to health-care facilities (mOR, 1.66; 95% CI, 1.12-2.48; P = .0126), and consumption of purchased groundwater (mOR, 1.50; 95% CI, 1.06-2.11; P = .0214) within 1 week preceding enrollment as independent factors associated with increased risk of salmonellosis. Hand-washing before meals (P = .0311), breastfeeding (P = .0370), consumption of chicken (P = .0019), and consumption of food prepared by caregivers (P = .0011) were protective against Salmonella infection. CONCLUSIONS: The principal transmission routes of Salmonella infection in Taiwanese children are person-to-person, waterborne, and environmental contacts. The possibility of powdered milk and groundwater contamination of Salmonella cannot be excluded and requires further investigation.
    日期: 2012-12
    關聯: Pediatric Infectious Disease Journal. 2012 Dec;31(12):E239-E243.
    Link to: http://dx.doi.org/10.1097/INF.0b013e31826ff592
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0891-3668&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000311794100002
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84865524307
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