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T cell proliferation and adaptive immune responses are critically regulated by protein phosphatase 4 |
Cell Cycle. 2016 Apr;15(8):1073-1083. |
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| 2016-04 |
Carboxyl-terminal fusion of E7 into Flagellin shifts TLR5 activation to NLRC4/NAIP5 activation and induces TLR5-independent anti-tumor immunity |
Scientific Reports. 2016 Apr;6:Article number 24199. |
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| 2016-04 |
Control of NF-kappa B activity, inflammation and stemness properties in cancer cells by Copper Metabolism (Murr1) Domain-Containing 1 |
The FASEB Journal. 2016 Apr;30(1, Suppl.):Meeting Abstract lb441. |
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| 2016-04 |
Thiostrepton inhibits Toll-like receptors 7, 8 and 9 mediated inflammatory responses |
The FASEB Journal. 2016 Apr;30(1, Suppl.):Meeting Abstract lb453. |
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| 2016-03-08 |
Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients |
Oncotarget. 2016 Mar 8;7(10):10976-10989. |
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| 2016-02-22 |
Guidelines for the use and interpretation of assays for monitoring autophagy [Erratum to: Autophagy. 2016 Jan 2;12(1):1-222.] |
Autophagy. 2016 Feb 22;12(2):443. |
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| 2016-02 |
Serum chemokine (CC motif) ligand 2 level as a diagnostic, predictive, and prognostic biomarker for prostate cancer |
Oncotarget. 2016 Feb;7(7):8389-8398. |
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| 2016-02 |
Quantum dots induced interferon beta expression via TRIF-dependent signaling pathways by promoting endocytosis of TLR4 |
Toxicology. 2016 Feb;344-346:61-70. |
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| 2016-01-02 |
Guidelines for the use and interpretation of assays for monitoring autophagy |
Autophagy. 2016 Jan 2;12(1):1-222. |
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| 2016-01 |
MAP4K family kinases in immunity and inflammation |
Advances in Immunology. 2016 Jan;129:277-314. |
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| 2016-01 |
TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity |
Cellular Signalling. 2016 Jan;28(1):145-151. |
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| 2015-12-28 |
Dual-specificity phosphatase 4 regulates STAT5 protein stability and helper T cell polarization |
PLoS ONE. 2015 Dec 28;10(12):Article number e0145880. |
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| 2015-11 |
Statin-conferred enhanced cellular resistance against bacterial pore-forming toxins in airway epithelial cells |
American Journal of Respiratory Cell and Molecular Biology. 2015 Nov;53(5):689-702. |
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| 2015-11 |
Ifit1 protects against lipopolysaccharide and D-galactosamine-induced fatal hepatitis by inhibiting activation of the JNK pathway |
Journal of Infectious Diseases. 2015 Nov 1;212(9):1509-1520. |
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| 2015-10 |
Identification of thiostrepton as a novel inhibitor for psoriasis-like inflammation induced by TLR7-9 |
Journal of Immunology. 2015 Oct;195(8):3912-3921. |
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| 2015-05-29 |
Lipidome and transcriptome profiling of pneumolysin intoxication identifies networks involved in statin-conferred protection of airway epithelial cells |
Scientific Reports. 2015 May 29;5:Article number 10624. |
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| 2015-05 |
Gene expression profiling and pathway network analysis predicts a novel antitumor function for a botanical-derived Drug, PG2 |
Evidence-Based Complementary and Alternative Medicine. 2015 May;2015:Article number 917345. |
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| 2015-04-15 |
IKKbeta enforces a LIN28B/TCF7L2 positive feedback loop that promotes cancer cell stemness and metastasis |
Cancer Research. 2015 Apr 15;75(8):1725-1735. |
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| 2014-12 |
Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination |
Autophagy. 2014 Dec;10(12):2239-2250. |
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| 2014-09-30 |
Development of CpG-Oligodeoxynucleotides for effective activation of rabbit TLR9 mediated immune responses |
PLoS ONE. 2014 Sep 30;9(9):Article number e108808. |
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| 2014-09-30 |
Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease |
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| 2014-09-12 |
PP4 is essential for germinal center formation and class switch recombination in mice |
PLoS ONE. 2014 Sep 12;9(9):Article number e107505. |
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| 2014-09 |
TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7 |
Vaccine. 2014 Sep;32(43):5593-5599. |
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HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance |
Nature Communications. 2014 Aug 6;5:Article number 4602. |
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| 2014-08 |
Outcomes and predictive factors of prostate cancer patients with extremely high prostate-specific antigen level |
Journal of Cancer Research and Clinical Oncology. 2014 Aug;140(8):1413-1419. |
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| 2014-06 |
MicroRNA-19a-3p inhibits breast cancer progression and metastasis by inducing macrophage polarization through downregulated expression of Fra-1 proto-oncogene |
Oncogene. 2014 Jun;33(23):3014-3023. |
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| 2014-05-07 |
Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity |
Cell and Bioscience. 2014 May 7;4:Article number 25. |
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| 2014-04-09 |
The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck |
Nature Communications. 2014 Apr 9;5:Article number 3618. |
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| 2014-03 |
The inducible Nitric-oxide Synthase (iNOS)/Src axis mediates toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon-beta synthesis in macrophages |
Journal of Biological Chemistry. 2014 Mar;289(13):9208-9220. |
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| 2014-02-15 |
Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation |
Journal of Immunology. 2014 Feb 15;192(4):1547-1557. |
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| 2014-02 |
The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1 |
Journal of Biological Chemistry. 2014 Feb 14;289(7):4009-4017. |
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Androgen receptor, ccl2, and epithelial-mesenchymal transition: A dangerous affair in the tumor microenvironment |
OncoImmunology. 2014 Jan;3(2):Article number e27871. |
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Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish |
Proceedings of the National Academy of Sciences of the United States of America. 2013 Dec;110(51):20711-20716. |
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TLR-induced PAI-2 expression suppresses IL-1beta processing via increasing autophagy and NLRP3 degradation |
Proceedings of the National Academy of Sciences of the United States of America. 2013 Oct;110(40):16079-16084. |
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| 2013-10 |
Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis |
Arthritis and Rheumatism. 2013 Oct;65(10):2573-2582. |
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| 2013-09-15 |
Infiltrating macrophages promote prostate tumorigenesis via modulating Androgen Receptor-Mediated CCL4-STAT3 signaling |
Cancer Research. 2013 Sep 15;73(18):5633-5646. |
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Regulation of thymocyte development by protein phosphatase 4 |
Cytokine. 2013 Sep;63(3):271-272. |
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Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation |
EMBO Molecular Medicine. 2013 Sep;5(9):1383-1401. |
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Phthalates suppress type I interferon in human plasmacytoid dendritic cells via epigenetic regulation |
Allergy. 2013 Jul;68(7):870-879. |
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The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination |
PLoS ONE. 2013 Jul;8(7):Article number e68804. |
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Quantum dots induced monocyte chemotactic protein-1 expression via MyD88-dependent Toll-like receptor signaling pathways in macrophages |
Toxicology. 2013 Jun;308:1-9. |
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Statins protect airway epithelium against bacterial pore-forming toxins |
American Journal of Respiratory and Critical Care Medicine. 2013 May 19;187:Meeting Abstract A6095. |
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MicroRNA-155 (miR-155) and interleukin 10 (IL-10) regulate proinflammatory cytokine response in orientia tsutsugamushi-infected human THP-1 macrophages |
Journal of Investigative Dermatology. 2013 May;133:S204. |
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Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway |
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The inhibition of HMG-CoA reductase pathway protects airway epithelial cells against bacterial pore-forming toxins |
Molecular Biology of the Cell. 2012 Dec;23:Article number 1371. |
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Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein |
Journal of Biological Chemistry. 2012 Oct 5;287(41):34091-34100. |
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| 2012-09-14 |
TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity |
Journal of Biological Chemistry. 2012 Sep 14;287(38):32216-32221. |
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| 2012-09 |
Activation of rabbit TLR9 by different CpG-ODN optimized for mouse and human TLR9 |
Comparative Immunology, Microbiology and Infectious Diseases. 2012 Sep;35(5):443-451. |
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Ligand recognition profiles of TLR9 from different species |
Cytokine. 2012 Sep;59(3):568. |
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Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker |
BMC Medicine. 2012 Aug 6;10(1):Article number 84. |
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